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PRMT5 gene

Known as: JAK-BINDING PROTEIN 1, ICLN-BINDING PROTEIN, 72-KD, PROTEIN ARGININE METHYLTRANSFERASE 5 
This gene is involved in both histone methylation and the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA).
National Institutes of Health

Papers overview

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2018
2018
An epigenetic drug screen was carried out in CRC organoids which identified PRMT5 as a potential epigenetic target regulating CC… 
2017
2017
Breast cancer is the second leading cause of cancer-related death in women, and approximately 70% of incidences are estrogen… 
2015
2015
The invention discloses a composition for inhibiting growth of osteosarcoma by targeting PRMT5 (protein arginine… 
2015
2015
PRMT5 is responsible for symmetric dimethylation of arginine residues in glycine and arginine rich (GAR) motifs on a variety of… 
2011
2011
Numerosi studi hanno mostrato come i meccanismi epigenetici di regolazione della cromatina svolgano un ruolo centrale nel…