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PRALIDOXIME IODIDE

Known as: pyridine-2-aldoxime methiodide 
National Institutes of Health

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pralidoxime

Papers overview

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2000
2000
Inhibition of acetylcholinesterase by (1S,3S)-isomalathion proceeds with loss of thiomethyl: kinetic and mass spectral evidence for an unexpected primary leaving group.
Previous work demonstrated kinetically that inhibition of mammalian acetylcholinesterase (AChE) by (1S)-isomalathions may proceed… 
Highly Cited
1972
Highly Cited
1972
QUANTITATIVE ASSAY OF ESTERASES IN END PLATES OF MOUSE DIAPHRAGM BY ELECTRON MICROSCOPE AUTORADIOGRAPHY
The inhibitor diisopropyl fluorophosphate (DFP) reacts covalently with a number of enzymes including acetylcholinesterase (AChE… 
1960
1960
In vivo reactivation by PAM of brain cholinesterase inhibited by paroaoxon.
Highly Cited
1959
Highly Cited
1959
Protection against lethal organophosphate poisoning by quaternary pyridine aldoximes.
The effect of 18 pyridinium aldoximes on diethylphosphoryl-acetocholinesterase in vitro and the protection against lethal… 
1958
1958
Use of oximes in the treatment of intoxication by anticholinesterase compounds in patients with myasthenia gravis.
1958
1958
The reactivation of cholinesterase inhibited with organophosphorus compounds. 2. Reactivation by pyridinealdoxime methiodides.
Material8 The pyridinealdoxime methiodides were obtained by boiling the oximes with methyl iodide in ethanol (Green & Saville… 
1958
1958
The effect of some oximes in sarin poisoning.
The effects of monoisonitrosoacetone (MINA), diacetylmonoxime (DAM) and pyridine-2-aldoxime methiodide (P2AM) upon the… 
1958
1958
Toxicity of diacetyl monoxime and of pyridine-2-aldoxime methiodide in man.
1958
1958
Overshoot and block of conduction by lipid-soluble acetylcholine analogues.
1958
1958
Designing of a new drug with antidotal properties against the nerve gas sarin.
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