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PPP2R5B gene

Known as: PP2A, B subunit, PR61 beta isoform, PROTEIN PHOSPHATASE 2, REGULATORY SUBUNIT B (B56), BETA, PR61B 
This gene plays a role in the negative control of cell growth and division.
National Institutes of Health

Related topics

Related topics

9 relations
Cell Proliferation Regulatory ProcessDNA ReplicationDephosphorylationHydrolysis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
MiR‐8‐3p regulates hyperthermia‐induced lactate secretion by targeting PPP2R5B in boar Sertoli cells
Lactate produced by glycolysis in Sertoli cells (SCs) is the main energy substrate for developing germ cells and plays a vital… 
2018
2018
Evidence of distinct RELN and TGFB1 genetic associations in familial and non-familial otosclerosis in a British population
Otosclerosis is a common form of hearing loss which typically presents in young adults. The disease has a familial, monogenic… 
Highly Cited
2015
Highly Cited
2015
Mutations in the PP2A regulatory subunit B family genes PPP2R5B, PPP2R5C and PPP2R5D cause human overgrowth
Overgrowth syndromes comprise a group of heterogeneous disorders characterised by excessive growth parameters, often in… 
2015
2015
Deletion of 11q12.3-11q13.1 in a patient with intellectual disability and childhood facial features resembling Cornelia de Lange syndrome.
2015
2015
Mutations in the PP 2 A regulatory subunit B family genes PPP 2 R 5 B , PPP 2 R 5 C and PPP 2 R 5 D cause human overgrowth
Overgrowth syndromes comprise a group of heterogeneous disorders characterised by excessive growth parameters, often in… 
2006
2006
Mutation analysis of five candidate genes in familial breast cancer
Most of the known breast cancer susceptibility genes (BRCA1, BRCA2, CHEK2 and ATM) are involved in the damage response pathway… 
Review
2004
Review
2004
The CD8 isoform CD8alphaalpha is not a functional homologue of the TCR co-receptor CD8alphabeta.
Although structurally similar, CD8alphabeta and CD8alphaalpha have notably diverted with regard to function. Whereas CD8alphabeta… 
2000
2000
Isolation and Characterization of par 1 1 and par 2 1 : Two Schizosaccharomyces pombe Genes Encoding B 9 Subunits of Protein Phosphatase 2 A
Protein phosphatase 2A (PP2A) is one of the major serine/threonine phosphatases found in eukaryotic cells. We cloned two genes… 
Highly Cited
1997
Highly Cited
1997
Identification of the multiple endocrine neoplasia type 1 (MEN1) gene. The European Consortium on MEN1.
Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder characterised by tumours of the parathyroids… 
1997
1997
Construction of a 1.2-Mb sequence-ready contig of chromosome 11q13 encompassing the multiple endocrine neoplasia type 1 (MEN1) gene. The European Consortium on MEN1.
Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant familial cancer syndrome characterized by parathyroid… 
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