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PPP2R1A gene

Known as: PR65A, PPP2R1A, protein phosphatase 2A, regulatory subunit A, alpha isoform 
This gene plays a role in the regulation of cell growth and division.
National Institutes of Health

Related topics

Related topics

12 relations
ApoptosisCell Proliferation Regulatory ProcessChromosome SegregationDNA Replication

Narrower (1)

PPP2R1A wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Das un- und dedifferenzierte Endometriumkarzinom
Das undifferenzierte Endometriumkarzinom (ECX) stellt eine epitheliale Neoplasie des Endometriums ohne eindeutige weitere… 
2018
2018
PPP2R1A regulated by PAX3/FOXO1 fusion contributes to the acquisition of aggressive behavior in PAX3/FOXO1-positive alveolar rhabdomyosarcoma
To better characterize the oncogenic role of the PAX3-FOXO1 fusion protein in the acquisition of aggressive behavior in ARMS, we… 
2018
2018
A 12 multigene NGS panel to characterize molecular biotypes in endometrial cancer.
5591Background: The Cancer Genome Atlas (TCGA) study for endometrial carcinomas (EC) defined four prognostic molecular biotypes… 
2015
2015
Ligand-directed targeting of lymphatic vessels uncovers mechanistic insights in melanoma metastasis
Significance Formation of metastasis is the most deadly step in melanoma progression and primarily occurs through the lymphatic… 
2015
2015
A7.11 IGA autoantigens – a link between the gut and the anti-TNF therapy response in rheumatoid arthritis patients analysed in two independent clinical trials
Background So far no mechanism for non response to biologicals targeting TNFα has been described, despite one third of rheumatoid… 
2015
2015
Endometrial and ovarian carcinoma-associated PPP2R1A mutations increase cancer cell aggressiveness through a dominant-negative mechanism
2013
2013
Functional Genetic Polymorphisms in PP2A Subunit Genes Confer Increased Risks of Lung Cancer in Southern and Eastern Chinese
Protein phosphatase-2A (PP2A) is one of the major cellular serine-threonine phosphatases and functions as a tumor suppressor that… 
Review
2012
Review
2012
430 Analysis of 2,700 Cancer Exomes to Identify Novel Cancer Drivers and Therapeutic Opportunities
2011
2011
Identification and functional analyses of polymorphism haplotypes of protein phosphatase 2A-Aα gene promoter.
2011
2011
Protein array screening reveals IgA autoantigenicity patterns predicting anti-TNFα therapy response in rheumatoid arthritis patients
Background One third of rheumatoid arthritis (RA) patients treated with biologicals targeting tumour necrosis factor α (TNFα) are… 
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