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PPM1H gene

Known as: KIAA1157, protein phosphatase, Mg2+/Mn2+ dependent 1H, neurite extension-related protein phosphatase related to PP2C 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Genes
Ppm1h protein, rat

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Down-regulation of PPM 1 H in papillary thyroid cancer inhibits cancer cell proliferation and invasion
Recent studies have confirmed that aberrant expression of protein phosphatase 1H (PPM1H) plays multiple roles in various types of… 
2016
2016
Analysis of Smad Phosphatase Activity In Vitro.
Phosphorylation of Smad1/5/8 at the C-terminal SXS motif by BMP type I receptors is one of the most critical events in BMP… 
Highly Cited
2011
Highly Cited
2011
PPM1H is a p27 phosphatase implicated in trastuzumab resistance.
The HER2 oncogene is overexpressed or amplified in 20% of breast cancers. HER2-positive cancer historically portends a poor… 
2011
2011
On the road to combinations of targeted therapies: PPM1H phosphatase as a suppressor of trastuzumab resistance.
Lee-Hoeflich and colleagues use RNA interference screening to identify the serine/threonine phosphatase PPM1H as an inhibitor of… 
2009
2009
Substrate-dependent metal preference of PPM1H, a cancer-associated protein phosphatase 2C: comparison with other family members
Protein phosphatase 2C (PP2C) family is characterized by requirement of metal cation for phosphatase activity. We previously… 
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