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PPIP5K2 gene

Known as: CFAP160, PPIP5K2, HISTIDINE ACID PHOSPHATASE DOMAIN-CONTAINING PROTEIN 1 
 

Topic mentions per year

Topic mentions per year

1998-2017
01219982017

Papers overview

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2015
2015
Identification of a functional nuclear translocation sequence in hPPIP5K2
Cells contain several inositol pyrophosphates (PP-InsPs; also known as diphosphoinositol polyphosphates), which play pivotal… (More)
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2015
2015
Whole exome sequencing in extended families with autism spectrum disorder implicates four candidate genes
Autism spectrum disorders (ASDs) are a group of neurodevelopmental disorders, characterized by impairment in communication and… (More)
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2014
2014
Synthetic Inositol Phosphate Analogs Reveal that PPIP5K2 Has a Surface-Mounted Substrate Capture Site that Is a Target for Drug Discovery
Diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) is one of the mammalian PPIP5K isoforms responsible for synthesis of… (More)
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2014
2014
Human Genome-Wide RNAi Screen Identifies an Essential Role for Inositol Pyrophosphates in Type-I Interferon Response
The pattern recognition receptor RIG-I is critical for Type-I interferon production. However, the global regulation of RIG-I… (More)
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2013
2013
The kinetic properties of a human PPIP5K reveal that its kinase activities are protected against the consequences of a deteriorating cellular bioenergetic environment
We obtained detailed kinetic characteristics--stoichiometry, reaction rates, substrate affinities and equilibrium conditions--of… (More)
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2012
2012
First synthetic analogues of diphosphoinositol polyphosphates: interaction with PP-InsP5 kinase.
We synthesised analogues of diphosphoinositol polyphosphates (PP-InsPs) in which the diphosphate is replaced by an… (More)
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2011
2011
Receptor-dependent compartmentalization of PPIP5K1, a kinase with a cryptic polyphosphoinositide binding domain.
The inositol pyrophosphates are multifunctional signalling molecules. One of the families of enzymes that synthesize the inositol… (More)
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2007
2007
Purification, sequencing, and molecular identification of a mammalian PP-InsP5 kinase that is activated when cells are exposed to hyperosmotic stress.
Mammalian cells utilize multiple signaling mechanisms to protect against the osmotic stress that accompanies plasma membrane ion… (More)
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2007
2007
Arabidopsis VIRE2 INTERACTING PROTEIN2 is required for Agrobacterium T-DNA integration in plants.
Agrobacterium tumefaciens-mediated genetic transformation is an efficient tool for genetic engineering of plants. VirE2 is a… (More)
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1998
1998
Site-Directed Mutagenesis of Human Vasoactive Intestinal Peptide Receptor Subtypes VIP1 and VIP2: Evidence for Difference in the Structure-Function Relationship PASCAL NICOLE, KAI DU, ALAIN COUVINEAU…
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Vasoactive intestinal peptide (VIP1 and VIP2) receptors belong to the new class II subfamily of G protein-coupled receptors. We… (More)
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