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PPIP5K2 gene

Known as: CFAP160, PPIP5K2, HISTIDINE ACID PHOSPHATASE DOMAIN-CONTAINING PROTEIN 1 
 
National Institutes of Health

Papers overview

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2018
2018
Mutations in Diphosphoinositol-Pentakisphosphate Kinase PPIP5K2 are associated with hearing loss in human and mouse
Autosomal recessive nonsyndromic hearing loss is a genetically heterogeneous disorder. Here, we report a severe-to-profound… Expand
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2017
2017
Effect of Interface Trap Charges on Performance Variation of Heterogeneous Gate Dielectric Junctionless-TFET
In this paper, we investigate the effect of interface trap charges on the variation of heterogeneous gate dielectric junctionless… Expand
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2017
2017
Impact of Interface Trap Charges on Performance of Electrically Doped Tunnel FET With Heterogeneous Gate Dielectric
In this paper, we investigate for the first time effect of positive (donor) and negative (acceptor) interface trap charges on the… Expand
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2015
2015
Identification of a functional nuclear translocation sequence in hPPIP5K2
BackgroundCells contain several inositol pyrophosphates (PP-InsPs; also known as diphosphoinositol polyphosphates), which play… Expand
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2014
2014
Synthetic Inositol Phosphate Analogs Reveal that PPIP5K2 Has a Surface-Mounted Substrate Capture Site that Is a Target for Drug Discovery
Summary Diphosphoinositol pentakisphosphate kinase 2 (PPIP5K2) is one of the mammalian PPIP5K isoforms responsible for synthesis… Expand
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2014
2014
Correction: Human Genome-Wide RNAi Screen Identifies an Essential Role for Inositol Pyrophosphates in Type-I Interferon Response
The pattern recognition receptor RIG-I is critical for Type-I interferon production. However, the global regulation of RIG-I… Expand
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2014
2014
Correction: Human Genome-Wide RNAi Screen Identifies an Essential Role for Inositol Pyrophosphates in Type-I Interferon Response
The pattern recognition receptor RIG-I is critical for Type-I interferon production. However, the global regulation of RIG-I… Expand
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2013
2013
The kinetic properties of a human PPIP5K reveal that its kinase activities are protected against the consequences of a deteriorating cellular bioenergetic environment
We obtained detailed kinetic characteristics--stoichiometry, reaction rates, substrate affinities and equilibrium conditions--of… Expand
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Highly Cited
2007
Highly Cited
2007
Purification, sequencing, and molecular identification of a mammalian PP-InsP5 kinase that is activated when cells are exposed to hyperosmotic stress.
Mammalian cells utilize multiple signaling mechanisms to protect against the osmotic stress that accompanies plasma membrane ion… Expand
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1997
1997
[Directed mutagenesis of human recombinant receptors of vasoactive intestinal peptide of VIP1 and VIP2 type. Difference in structure-activity relationship].
OBJECTIVES Two vasoactive intestinal peptide (VIP) receptor subtypes have been cloned. We studied the structure-function… Expand
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