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PPID protein, human

Known as: Cyp40 protein, human, cyclophilin D protein, human, 40 kDa Peptidyl-Prolyl Cis-Trans Isomerase 
Peptidyl-prolyl cis-trans isomerase D (370 aa, ~41 kDa) is encoded by the human PPID gene. This protein plays a role in the isomerization of imidic… 
National Institutes of Health

Related topics

Related topics

7 relations
Chaperone Protein Interaction ProcessEnzyme GeneMolecular ChaperonesPPID gene

Broader (2)

Cyclophilinscyclophilin D

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
High Cyclophilin D Content of Synaptic Mitochondria Results in Increased Vulnerability to Permeability Transition
Mitochondria isolated from synaptosomes are more sensitive to Ca2+ overload and the resultant opening of the mitochondrial… 
Highly Cited
2004
Highly Cited
2004
Cyclophilin-D promotes the mitochondrial permeability transition but has opposite effects on apoptosis and necrosis.
Cyclophilin-D is a peptidylprolyl cis-trans isomerase of the mitochondrial matrix. It is involved in mitochondrial permeability… 
Highly Cited
2002
Highly Cited
2002
Mitochondrial Targeted Cyclophilin D Protects Cells from Cell Death by Peptidyl Prolyl Isomerization*
Cyclophilin D (CyPD) is thought to sensitize opening of the mitochondrial permeability transition pore (mPTP) based on the… 
Highly Cited
2001
Highly Cited
2001
CD147 is a signaling receptor for cyclophilin B.
Cyclophilins A and B (CyPA and CyPB) are cyclosporin A binding proteins that can be secreted in response to inflammatory stimuli… 
Highly Cited
1998
Highly Cited
1998
Point mutations in v-Myb disrupt a cyclophilin-catalyzed negative regulatory mechanism.
Highly Cited
1998
Highly Cited
1998
Requirement for Hsp90 and a CyP-40-type Cyclophilin in Negative Regulation of the Heat Shock Response*
The heat shock response is a highly conserved mechanism that allows cells to withstand a variety of stress conditions. Activation… 
Highly Cited
1996
Highly Cited
1996
Molecular Chaperone Machines: Chaperone Activities of the Cyclophilin Cyp-40 and the Steroid Aporeceptor-Associated Protein p23
Molecular chaperones are essential proteins that participate in the regulation of steroid receptors in eukaryotes. The steroid… 
Highly Cited
1996
Highly Cited
1996
Cyclophilin 40 (CyP-40), Mapping of Its hsp90 Binding Domain and Evidence That FKBP52 Competes with CyP-40 for hsp90 Binding (*)
The structurally related immunophilins cyclophilin 40 (CyP-40) and FKBP52 have been identified as components of the unactivated… 
Highly Cited
1995
Highly Cited
1995
The Cyclosporin A-binding Immunophilin CyP-40 and the FK506-binding Immunophilin hsp56 Bind to a Common Site on hsp90 and Exist in Independent Cytosolic Heterocomplexes with the Untransformed…
We have recently shown that hsp56, the FK506-binding immunophilin component of both the heat shock protein (hsp90•hsp70•hsp56… 
Highly Cited
1993
Highly Cited
1993
The cyclophilin component of the unactivated estrogen receptor contains a tetratricopeptide repeat domain and shares identity with p59 (FKBP59).
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