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Obesity originates from a failure of the body-weight control systems, which may be affected by changing environmental influences… Expand The three peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors of the nuclear hormone… Expand This study investigated the effects of cyclic stretching on adipocyte differentiation of mouse preadipocyte 3T3-L1 cells… Expand Transforming growth factor (TGF)-β is a potent inhibitor of adipocyte differentiation. To identify which adipocyte transcription… Expand The mechanism whereby lovastatin can counteract steroid-induced osteonecrosis and osteoporosis is poorly understood. We assessed… Expand Cells of the bone marrow stroma can reversibly convert among different phenotypes. Based on this and on evidence for a reciprocal… Expand The peroxisome proliferator-activated receptors (PPARs) are a subgroup of nuclear receptors activated by fatty acids and… Expand Adipocyte differentiation is driven by the expression and activation of three transcription factor families: the differentially… Expand PPARγ is a member of the PPAR subfamily of nuclear receptors. In this work, the structure of the human PPARγ cDNA and gene was… Expand We describe the cloning, characterization, and tissue distribution of the two human peroxisome proliferator activated receptor… Expand