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PON1 gene

Known as: PARAOXONASE, PLASMA, ESTERASE A, PON1 
This gene plays a role in the metabolism of organophosphates, lactones and aromatic carboxylic acid esters.
National Institutes of Health

Related topics

Related topics

10 relations
ArylesteraseDephosphorylationEPCAM geneHydrolysis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Relation of plasma protein oxidation parameters and paraoxonase activity in the ageing population
The incidence of atherosclerosis increases with age. Oxidative changes in proteins and lipids are considered to be among the… 
Highly Cited
2006
Highly Cited
2006
The correlation of homocysteine-thiolactonase activity of the paraoxonase (PON1) protein with coronary heart disease status.
Homocysteine (Hcy)-thiolactonase (HTase) activity of the paraoxonase-1 (PON1) protein detoxifies Hcythiolactone in human blood… 
Highly Cited
2005
Highly Cited
2005
Seamless integration of an 8/spl times/2.5 Gb/s WDM-PON and radio-over-fiber using all-optical up-conversion based on Raman-assisted FWM
We experimentally demonstrate the seamless integration of an 8/spl times/2.5 Gb/s wavelength-division-multiplexing passive… 
Highly Cited
2005
Highly Cited
2005
Indications that paraoxonase-1 contributes to plasma high density lipoprotein levels in familial hypercholesterolemia Published, JLR Papers in Press, December 1, 2004. DOI 10.1194/jlr.M400052-JLR200
HDL-associated paraoxonase type 1 (PON1) can protect LDL and HDL against oxidative modification in vitro and therefore may… 
Highly Cited
2003
Highly Cited
2003
Interrelationship of smoking, paraoxonase activity, and leisure time physical activity: a population-based study.
Highly Cited
2002
Highly Cited
2002
Proinflammatory Cytokines But Not Acute Phase Serum Amyloid A Or C-Reactive Protein, Downregulate Paraoxonase 1 (Pon1) Expression By Hepg2 Cells
The expression of paraoxonase1 (PON1) during inflammation has been investigated in vitro. The alteration of steady state PON1… 
Review
2000
Review
2000
Genetic and temporal determinants of pesticide sensitivity: role of paraoxonase (PON1).
Susceptibility to organophosphorus (OP) insecticides and nerve agents is strongly influenced by genetic and developmental factors… 
Highly Cited
2000
Highly Cited
2000
Dietary fat modulates serum paraoxonase 1 activity in rats.
We examined the effects of dietary fats with specific fatty acid compositions, on serum paraoxonase (PON1) activity in rats. Male… 
Highly Cited
1999
Highly Cited
1999
Paraoxonase gene polymorphisms are associated with carotid arterial wall thickness in subjects with familial hypercholesterolemia.
Highly Cited
1998
Highly Cited
1998
Genetic variation in paraoxonase-1 and paraoxonase-2 is associated with variation in plasma lipoproteins in Alberta Hutterites.
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