PMX 464

Known as: PMX-464, PMX464 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2006-2016
012320062016

Papers overview

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2016
2016
Thioredoxin (Trx) is an oxidoreductase with important physiological function. Imbalances in the NADPH/thioredoxin reductase… (More)
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2011
2011
Better drugs are urgently needed for the treatment of African sleeping sickness. We tested a series of promising anticancer… (More)
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2011
2011
Thioredoxin (Trx) plays a critical role in the regulation of cellular redox homeostasis. Many disease causing pathogens rely on… (More)
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2010
2010
The induction of phase 2 and antioxidant enzymes via the transcription factor Nuclear factor-erythroid 2-related factor 2 (Nrf2… (More)
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2009
2009
  • Wong P.W, Yong Loo Lin
  • 2009
Cancer chemoprevention has gained more and more attention over the past 25 years and has been successful in many in vitro and in… (More)
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2008
2008
BACKGROUND AND PURPOSE Subtle changes in the intracellular reduction-oxidation (redox) state can modulate nuclear factor-kappaB… (More)
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Review
2008
Review
2008
Thioredoxin is a redox-sensitive molecule that has pleiotropic cellular effects, such as the control of proliferation, redox… (More)
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2008
2008
Increasing evidence places the epithelial cell at the centre of inflammatory processes in human airways. Crucial to this function… (More)
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2007
2007
BACKGROUND AND PURPOSE PMX464 is a novel benzothiazole substituted cyclohexadienone reportedly targeting the thioredoxin (Trx1… (More)
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2006
2006
The synthesis and in vitro antitumour evaluation of a new series of fluorinated benzothiazole-substituted 4-hydroxycyclohexa-2,5… (More)
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