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PMX 464

Known as: PMX-464, PMX464 
 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

BenzothiazolesHydroquinones

Papers overview

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Highly Cited
2009
Highly Cited
2009
URINARY LIVER-TYPE FATTY ACID-BINDING PROTEIN IN SEPTIC SHOCK: EFFECT OF POLYMYXIN B-IMMOBILIZED FIBER HEMOPERFUSION
We aimed to determine retrospectively whether urinary liver-type fatty acid-binding protein (L-FABP) levels are altered in… Expand
Highly Cited
2008
Highly Cited
2008
Polymyxin-B hemoperfusion inactivates circulating proapoptotic factors
ObjectiveTo test the hypothesis that extracorporeal therapy with polymyxin B (PMX-B) may prevent Gram-negative sepsis-induced… Expand
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Highly Cited
2004
Highly Cited
2004
Hemoperfusion with polymyxin B-immobilized fibers reduced the number of CD16+CD14 + monocytes in patients with septic shock
Background: CD16 +CD14+ monocytes dramatically increase in number in patients with severe infection. Hemoperfusion with PMX-F… Expand
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Highly Cited
2004
Highly Cited
2004
Effect of Polymyxin B-Immobilized Fiber on Blood Metalloproteinase-9 and Tissue Inhibitor of Metalloproteinase-1 Levels in Acute Respiratory Distress Syndrome Patients
Background/Aims: Metalloproteinase (MMP)-9 plays a role in the pathogenesis of acute respiratory distress syndrome (ARDS… Expand
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Highly Cited
2002
Highly Cited
2002
Endotoxin removal by direct hemoperfusion with an adsorbent column using polymyxin B-immobilized fiber ameliorates systemic circulatory disturbance in patients with septic shock.
Direct hemoperfusion (DHP) with an adsorbent column using polymyxin B-immobilized fiber (PMX-F) has been shown to improve the… Expand
Highly Cited
1999
Highly Cited
1999
Treatment with polymyxin B-immobilized fiber reduces platelet activation in septic shock patients: Decrease in plasma levels of soluble P-selectin, platelet factor 4 and β-thromboglobulin
Objective: To clarify whether plasma concentrations of soluble P-selectin, platelet factor-4 (PF-4) and β-thromboglobulin (βTG… Expand
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Highly Cited
1998
Highly Cited
1998
Modulation of plasma metalloproteinase-9 concentrations and peripheral blood monocyte mRNA levels in patients with septic shock: effect of fiber-immobilized polymyxin B treatment.
The authors measured plasma metalloproteinase (MMP)-9 and corresponding monocyte mRNA in 20 patients with septic shock. Plasma… Expand
1998
1998
Changes in plasma erythropoietin and interleukin-6 concentrations in patients with septic shock after hemoperfusion with polymyxin B-immobilized fiber
Objective: To find out whether polymyxin B-immobilized fiber (PMX-F) treatment affects the clinical parameters and plasma… Expand
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1991
1991
Endotoxin filtration and immune stimulation improve survival from gram-negative sepsis.
Polymyxin B, when bound to a polystyrene fiber (PMX-F), has been used experimentally as an extracorporeal blood filter to reduce… Expand
Highly Cited
1989
Highly Cited
1989
New approach to endotoxic and septic shock by means of polymyxin B immobilized fiber.
Endotoxin shock therapy has not been successfully dealt with pharmacologically. Circulation of endotoxins in the blood is an… Expand
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