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PMX 464

Known as: PMX-464, PMX464 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

BenzothiazolesHydroquinones

Papers overview

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Highly Cited
2009
Highly Cited
2009
URINARY LIVER-TYPE FATTY ACID-BINDING PROTEIN IN SEPTIC SHOCK: EFFECT OF POLYMYXIN B-IMMOBILIZED FIBER HEMOPERFUSION
We aimed to determine retrospectively whether urinary liver-type fatty acid-binding protein (L-FABP) levels are altered in… 
Highly Cited
2008
Highly Cited
2008
Polymyxin-B hemoperfusion inactivates circulating proapoptotic factors
ObjectiveTo test the hypothesis that extracorporeal therapy with polymyxin B (PMX-B) may prevent Gram-negative sepsis-induced… 
Review
2008
Review
2008
The thioredoxin system: a key target in tumour and endothelial cells.
Thioredoxin is a redox-sensitive molecule that has pleiotropic cellular effects, such as the control of proliferation, redox… 
Review
2007
Review
2007
Effectiveness of polymyxin B-immobilized fiber column in sepsis: a systematic review
IntroductionSevere sepsis and septic shock are common problems in the intensive care unit and carry a high mortality. Endotoxin… 
Highly Cited
2004
Highly Cited
2004
Hemoperfusion with polymyxin B-immobilized fibers reduced the number of CD16+CD14 + monocytes in patients with septic shock
Background: CD16 +CD14+ monocytes dramatically increase in number in patients with severe infection. Hemoperfusion with PMX-F… 
Highly Cited
2004
Highly Cited
2004
Effect of Polymyxin B-Immobilized Fiber on Blood Metalloproteinase-9 and Tissue Inhibitor of Metalloproteinase-1 Levels in Acute Respiratory Distress Syndrome Patients
Background/Aims: Metalloproteinase (MMP)-9 plays a role in the pathogenesis of acute respiratory distress syndrome (ARDS… 
Highly Cited
2002
Highly Cited
2002
Endotoxin removal by direct hemoperfusion with an adsorbent column using polymyxin B-immobilized fiber ameliorates systemic circulatory disturbance in patients with septic shock.
Direct hemoperfusion (DHP) with an adsorbent column using polymyxin B-immobilized fiber (PMX-F) has been shown to improve the… 
Highly Cited
1999
Highly Cited
1999
Treatment with polymyxin B-immobilized fiber reduces platelet activation in septic shock patients: Decrease in plasma levels of soluble P-selectin, platelet factor 4 and β-thromboglobulin
Objective: To clarify whether plasma concentrations of soluble P-selectin, platelet factor-4 (PF-4) and β-thromboglobulin (βTG… 
Highly Cited
1998
Highly Cited
1998
Modulation of plasma metalloproteinase-9 concentrations and peripheral blood monocyte mRNA levels in patients with septic shock: effect of fiber-immobilized polymyxin B treatment.
Highly Cited
1989
Highly Cited
1989
New approach to endotoxic and septic shock by means of polymyxin B immobilized fiber.
Endotoxin shock therapy has not been successfully dealt with pharmacologically. Circulation of endotoxins in the blood is an… 
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