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PLZF-RARalpha fusion protein, human
Known as:
PLZF-RARalpha
, PLZF-RARalpha Fusion Protein
, PLZF/RARa Protein
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A fusion protein encoded by the ZBTB16/RARA fusion gene. This protein is comprised of the N-terminal POZ domain and two of the nine zinc fingers of…
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National Institutes of Health
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Related topics
Related topics
5 relations
Fusion Gene
RARA/ZBTB16 Fusion Protein
Transcription Repressor/Corepressor
ZBTB16/RARA Fusion Gene
Broader (1)
Oncogene Proteins, Fusion
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Interaction between nuclear localization signal-retinoic acid receptor alpha and Ubiquilin 1.
Dan Zhu
,
Chong Wang
,
Beizhong Liu
,
Yan Wu
,
L. Zhong
,
Chun-guang Wang
Zhong nan da xue xue bao. Yi xue ban = Journal of…
2010
Corpus ID: 39773107
OBJECTIVE To identify the interaction between nuclear localization signal-retinoic acid receptor alpha (NLS-RARalpha) and…
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Highly Cited
2009
Highly Cited
2009
Comprehensive genomic screens identify a role for PLZF-RARalpha as a positive regulator of cell proliferation via direct regulation of c-MYC.
K. Rice
,
I. Hormaeche
,
+9 authors
J. Licht
Blood
2009
Corpus ID: 15133957
The t(11;17)(q23;q21) translocation is associated with a retinoic acid (RA)-insensitive form of acute promyelocytic leukemia (APL…
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2008
2008
Detection of PLZF- RARa fusion in patients with Acute Promyelocytic Leukemia
M. Araghi
,
K. Alimoghadam
,
+4 authors
A. Ghavamzadeh
2008
Corpus ID: 54702389
هديكچ فده و هنيمز : داح يتيسوليمورپ يمسول (APL) يموزومورك يياجباج اب t(15:17) ) نژ رـگ قاـحلا ياـه PML و RAR…
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2005
2005
[hCG-PLZF-RARalpha/hCG-RARalpha-PLZF transgenic mice developing into leukemia].
Li-juan Chen
,
Ying Dong
,
+6 authors
Saijuan Chen
Zhongguo shi yan xue ye xue za zhi
2005
Corpus ID: 20823376
To investigate the potential role and the mechanism of PLZF-RARalpha/RARalpha-PLZF double fusion gene in the pathogenesis of…
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2004
2004
Monitoring ligand-mediated nuclear receptor-coregulator interactions by noncovalent mass spectrometry.
Sarah Sanglier
,
W. Bourguet
,
+5 authors
A. van Dorsselaer
European Journal of Biochemistry
2004
Corpus ID: 25812619
Retinoid receptors are ligand-dependent transcription factors belonging to the nuclear receptor superfamily. Retinoic acid…
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2002
2002
The Retinoic Acid Receptor ( RAR ) Chimeric Proteins PML-, PLZF-, NPM-, and NuMA-RAR Have Distinct Intracellular Localization Patterns 1
J. Hummel
,
Tong Zhang
,
R. Wells
,
S. Kamel‐Reid
2002
Corpus ID: 1904955
Retinoic acid receptor (RAR ) gene rearrangement by reciprocal chromosome translocation is the molecular signature of acute…
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Review
2001
Review
2001
Acute promyelocytic leukemia with a PLZF-RARalpha fusion protein.
J. Jansen
,
B. Löwenberg
Seminars in hematology (Print)
2001
Corpus ID: 21104704
In most cases of acute promyelocytic leukemia (APL), a fusion of the promyelocytic leukemia (PML) and the retinoic acid receptor…
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2000
2000
Critical role of the H6-H7 loop in the conformational adaptation of all-trans retinoic acid and synthetic retinoids within the ligand-binding site of RARalpha.
S. Mailfait
,
E. Thoreau
,
D. Belaiche
,
P. Formstecher And B Sablonniè
Journal of Molecular Endocrinology
2000
Corpus ID: 42976388
The pleiotropic effects of the natural and synthetic retinoids are mediated by the activation of the two subfamilies of nuclear…
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1997
1997
[Study of dominant negative effect of the PLZF-RARalpha against the wild-type RARalpha in acute promyelocytic leukemia].
S. Dong
,
J. Zhu
,
+4 authors
L. Chen
Zhonghua xue ye xue za zhi = Zhonghua xueyexue…
1997
Corpus ID: 45252276
OBJECTIVE To explore the role of promyelocytic leukemia zinc finger (PLZF) gene on 11q23 and RARalpha gene on 17q21. METHODS…
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1997
1997
[Comparative study of two fusion retinoic acid receptor alpha in acute promyelocytic leukemia].
H. Zhong
,
S. Dong
,
+7 authors
L. Chen
Zhonghua xue ye xue za zhi = Zhonghua xueyexue…
1997
Corpus ID: 12156212
OBJECTIVE To make a comparison of biological properties between PML-RARalpha and PLZF-RARalpha fusion proteins. METHODS…
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