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PLZF-RARalpha fusion protein, human

Known as: PLZF-RARalpha, PLZF-RARalpha Fusion Protein, PLZF/RARa Protein 
A fusion protein encoded by the ZBTB16/RARA fusion gene. This protein is comprised of the N-terminal POZ domain and two of the nine zinc fingers of… 
National Institutes of Health

Related topics

Related topics

5 relations
Fusion GeneRARA/ZBTB16 Fusion ProteinTranscription Repressor/CorepressorZBTB16/RARA Fusion Gene

Broader (1)

Oncogene Proteins, Fusion

Papers overview

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2010
2010
Interaction between nuclear localization signal-retinoic acid receptor alpha and Ubiquilin 1.
OBJECTIVE To identify the interaction between nuclear localization signal-retinoic acid receptor alpha (NLS-RARalpha) and… 
Highly Cited
2009
Highly Cited
2009
Comprehensive genomic screens identify a role for PLZF-RARalpha as a positive regulator of cell proliferation via direct regulation of c-MYC.
The t(11;17)(q23;q21) translocation is associated with a retinoic acid (RA)-insensitive form of acute promyelocytic leukemia (APL… 
2008
2008
Detection of PLZF- RARa fusion in patients with Acute Promyelocytic Leukemia
هديكچ فده و هنيمز : داح يتيسوليمورپ يمسول (APL) يموزومورك يياجباج اب t(15:17) ) نژ رـگ قاـحلا ياـه PML و RAR… 
2005
2005
[hCG-PLZF-RARalpha/hCG-RARalpha-PLZF transgenic mice developing into leukemia].
To investigate the potential role and the mechanism of PLZF-RARalpha/RARalpha-PLZF double fusion gene in the pathogenesis of… 
2004
2004
Monitoring ligand-mediated nuclear receptor-coregulator interactions by noncovalent mass spectrometry.
Retinoid receptors are ligand-dependent transcription factors belonging to the nuclear receptor superfamily. Retinoic acid… 
2002
2002
The Retinoic Acid Receptor ( RAR ) Chimeric Proteins PML-, PLZF-, NPM-, and NuMA-RAR Have Distinct Intracellular Localization Patterns 1
Retinoic acid receptor (RAR ) gene rearrangement by reciprocal chromosome translocation is the molecular signature of acute… 
Review
2001
Review
2001
Acute promyelocytic leukemia with a PLZF-RARalpha fusion protein.
In most cases of acute promyelocytic leukemia (APL), a fusion of the promyelocytic leukemia (PML) and the retinoic acid receptor… 
2000
2000
Critical role of the H6-H7 loop in the conformational adaptation of all-trans retinoic acid and synthetic retinoids within the ligand-binding site of RARalpha.
The pleiotropic effects of the natural and synthetic retinoids are mediated by the activation of the two subfamilies of nuclear… 
1997
1997
[Study of dominant negative effect of the PLZF-RARalpha against the wild-type RARalpha in acute promyelocytic leukemia].
  • S. DongJ. Zhu L. Chen
  • Zhonghua xue ye xue za zhi = Zhonghua xueyexue…
  • 1997
  • Corpus ID: 45252276
OBJECTIVE To explore the role of promyelocytic leukemia zinc finger (PLZF) gene on 11q23 and RARalpha gene on 17q21. METHODS… 
1997
1997
[Comparative study of two fusion retinoic acid receptor alpha in acute promyelocytic leukemia].
OBJECTIVE To make a comparison of biological properties between PML-RARalpha and PLZF-RARalpha fusion proteins. METHODS… 
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