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PLEKHA5 gene

Known as: PLEKHA5, KIAA1686, pleckstrin homology domain containing A5 
 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Genes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
A Large-Scale Genome-Wide Association Study in U.S. Holstein Cattle
Genome-wide association study (GWAS) is a powerful approach to identify genomic regions and genetic variants associated with… Expand
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2019
2019
High genetic risk scores of SLIT3, PLEKHA5 and PPP2R2C variants increased insulin resistance and interacted with coffee and caffeine consumption in middle-aged adults.
BACKGROUNDS AND AIMS Insulin resistance is a common feature of metabolic syndrome that may be influenced by genetic risk factors… Expand
2019
2019
PLEKHA5 regulates tumor growth in metastatic melanoma
PLEKHA5 has previously been identified as a novel molecule implicated in melanoma brain metastasis, a disease that continues to… Expand
Review
2018
Review
2018
Deciphering mechanisms of brain metastasis in melanoma - the gist of the matter
  • T. Redmer
  • Molecular Cancer
  • 2018
    • Corpus ID: 51727317
Metastasis to distant organs and particularly the brain still represents the most serious obstacle in melanoma therapies… Expand
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2018
2018
Mutations in the Epithelial Cadherin-p120-Catenin Complex Cause Mendelian Non-Syndromic Cleft Lip with or without Cleft Palate.
Non-syndromic cleft lip with or without cleft palate (NS-CL/P) is one of the most common human birth defects and is generally… Expand
2018
2018
New susceptibility loci for cutaneous melanoma risk and progression revealed using a porcine model
Despite major advances, it is estimated that a large part of melanoma predisposing genes remains to be discovered. Animal models… Expand
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2016
2016
Targeted next generation sequencing approach identifies eighteen new candidate genes in normosmic hypogonadotropic hypogonadism and Kallmann syndrome
The genetic basis is unknown for ∼60% of normosmic hypogonadotropic hypogonadism (nHH)/Kallmann syndrome (KS). DNAs from (17 male… Expand
2015
2015
PLEKHA5: A Key to Unlock the Blood–Brain Barrier?
Brain metastases represent a devastating complication of melanoma. Our understanding of the mechanisms driving metastasis to the… Expand
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2014
2014
PLEKHA5 as a Biomarker and Potential Mediator of Melanoma Brain Metastasis
Purpose: Approximately 40% of patients with metastatic melanoma develop brain metastases. Our purpose was to identify genes… Expand
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2012
2012
Identification and characterization of splicing variants of PLEKHA5 (Plekha5) during brain development.
PLEKHA5 (pleckstrin homology domain-containing protein family A, member 5) belongs to the PLEKHA family (PLEKHA1-6); however, the… Expand
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