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PLEKHA5 gene

Known as: PLEKHA5, KIAA1686, pleckstrin homology domain containing A5 
National Institutes of Health

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Broader (1)

Genes

Papers overview

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Highly Cited
2019
Highly Cited
2019
A Large-Scale Genome-Wide Association Study in U.S. Holstein Cattle
Genome-wide association study (GWAS) is a powerful approach to identify genomic regions and genetic variants associated with… 
2019
2019
High genetic risk scores of SLIT3, PLEKHA5 and PPP2R2C variants increased insulin resistance and interacted with coffee and caffeine consumption in middle-aged adults.
2019
2019
PLEKHA5 regulates tumor growth in metastatic melanoma
PLEKHA5 has previously been identified as a novel molecule implicated in melanoma brain metastasis, a disease that continues to… 
Highly Cited
2018
Highly Cited
2018
Mutations in the Epithelial Cadherin-p120-Catenin Complex Cause Mendelian Non-Syndromic Cleft Lip with or without Cleft Palate.
Review
2018
Review
2018
Deciphering mechanisms of brain metastasis in melanoma - the gist of the matter
  • T. Redmer
  • Molecular Cancer
  • 2018
  • Corpus ID: 51727317
Metastasis to distant organs and particularly the brain still represents the most serious obstacle in melanoma therapies… 
Review
2017
Review
2017
Management of intracranial melanomas in the era of precision medicine.
Melanoma is the most lethal of skin cancers, in part because of its proclivity for rapid and distant metastasis. It is also… 
Highly Cited
2016
Highly Cited
2016
Targeted next generation sequencing approach identifies eighteen new candidate genes in normosmic hypogonadotropic hypogonadism and Kallmann syndrome
2015
2015
PLEKHA5: A Key to Unlock the Blood–Brain Barrier?
Brain metastases represent a devastating complication of melanoma. Our understanding of the mechanisms driving metastasis to the… 
Highly Cited
2014
Highly Cited
2014
PLEKHA5 as a Biomarker and Potential Mediator of Melanoma Brain Metastasis
Purpose: Approximately 40% of patients with metastatic melanoma develop brain metastases. Our purpose was to identify genes… 
2013
2013
A likely role for the PH-domain containing protein, PEPP2/ PLEKHA5, at the membrane-microtubule cytoskeleton interface
PH (pleckstrin homology) domains are well known to bind membrane phosphoinositides with different specificities and direct PH… 
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