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PLA2G7 wt Allele

Known as: LP-PLA2, PAFAD, PAFAH 
Human PLA2G7 wild-type allele is located within 6p21.2-p12 and is approximately 31 kb in length. This allele, which encodes platelet-activating… 
National Institutes of Health

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Related topics

3 relations
HydrolysisLIS1 PathwayLipid Metabolism

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Genetic heterogeneity of platelet glycoproteins Ia and IIIa and the risk of spontaneous miscarriages
Abstract Objective: The aim of this study was to investigate the association between the genetic heterogeneity of platelet… 
2016
2016
Lipoprotein-associated phospholipase A2: a new marker to determine cardiovascular risk in hypercholesterolemic dyslipidaemic children
Background Inflammation and hypercholesterolaemia contribute to atherosclerotic changes which can start in childhood. Children… 
2015
2015
The 12th World Congress on Inflammation
Background: A model of gout which consists of human blood derived in vitro differentiated monocytes/macrophages and neutrophils… 
2013
2013
Effect of darapladib on plasma lipoprotein-associated phospholipase A2 activity in Japanese dyslipidemic patients, with exploratory analysis of a PLA2G7 gene polymorphism of Val279Phe.
BACKGROUND  Lipoprotein-associated phospholipase A2 (Lp-PLA2) is being evaluated as a therapeutic target for treatment of… 
2013
2013
Correlation between plasma lipoprotein-associated phospholipase A2 and peripheral arterial disease
Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a recently identified and potentially useful plasma biomarker for… 
2010
2010
Identification of the G994T polymorphism in exon 9 of plasma platelet-activating factor acetylhydrolase gene as a risk factor for polycystic ovary syndrome.
BACKGROUND Low-grade chronic inflammation and greater risks of cardiovascular diseases are often present in patients with… 
Highly Cited
2005
Highly Cited
2005
Effects of atorvastatin versus other statins on fasting and postprandial C-reactive protein and lipoprotein-associated phospholipase A2 in patients with coronary heart disease versus control subjects…
2004
2004
Functional impairment of two novel mutations detected in lipoprotein-associated phospholipase A2 (Lp-PLA2) deficiency patients
AbstractPlasma lipoprotein-associated phospholipase A2 (Lp-PLA2), also known as platelet-activating factor (PAF) acetylhydrolase… 
1998
1998
Positive Darwinian selection in Vipera palaestinae phospholipase A2 genes is unexpectedly limited to the third exon.
The venom of Vipera palaestinae contains a two-component toxin, consisting of an acidic phospholipase A2 (PLA2) and a basic… 
Highly Cited
1994
Highly Cited
1994
Arachidonyl trifluoromethyl ketone, a potent inhibitor of 85-kDa phospholipase A2, blocks production of arachidonate and 12-hydroxyeicosatetraenoic acid by calcium ionophore-challenged platelets.
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