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PLA2G1B wt Allele

Known as: Phospholipase A2, Group IB (Pancreas) wt Allele, PLA2, PLA2A 
Human PLA2G1B wild-type allele is located within 12q23-q24.1 and is approximately 6 kb in length. This allele, which encodes phospholipase A2 protein… 
National Institutes of Health

Related topics

Related topics

10 relations
12q23-q24.1Arachidonic Acid Metabolism PathwayHydrolysisImmune response
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Papers overview

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2009
2009
Enzymatic and structural characterization of new PLA2 isoform isolated from white venom of Crotalus durissus ruruima.
This work reports the structural and enzymatic characterization of a new sPLA2 from the white venom of Crotalus durissus ruruima… 
2006
2006
PGE2 amplifies the effects of IL‐1β on vascular smooth muscle cell de‐differentiation: A consequence of the versatility of PGE2 receptors 3 due to the emerging expression of adenylyl cyclase 8
Transition of vascular smooth muscle cells from a contractile/quiescent to a secretory/proliferative phenotype is one of the… 
Highly Cited
2004
Highly Cited
2004
Biosynthesis of anandamide and N-palmitoylethanolamine by sequential actions of phospholipase A2 and lysophospholipase D.
Anandamide (an endocannabinoid) and other bioactive long-chain NAEs (N-acylethanolamines) are formed by direct release from N… 
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1999
1999
Distal hereditary motor neuropathy type II (distal HMN type II): phenotype and molecular genetics.
The distal hereditary motor neuropathies (distal HMN) are clinically and genetically heterogeneous and are subdivided in seven… 
1998
1998
Nuclear location of PLA2-I in proliferative cells.
We have previously demonstrated that pancreatic PLA2 (PLA2-I) stimulates the proliferation of UIII cells, a stromal cell line… 
Highly Cited
1997
Highly Cited
1997
Depletion of Human Monocyte 85-kDa Phospholipase A2 Does Not Alter Leukotriene Formation*
Human monocytes possess several acylhydrolase activities and are capable of producing both prostanoids (PG) and leukotriene (LT… 
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1997
1997
Mutation analysis of the human pancreatic phospholipase A2 gene in a family with distal hereditary motor neuropathy type II linked to 12q24
Molecular genetic analysis in a Belgian family with distal hereditary motor neuropathy type II (distal HMN II), demonstrated… 
1996
1996
Association study of bipolar disorder at the phospholipase A2 gene (PLA2A) in the Darier's disease (DAR) region of chromosome 12q23‐q24.1
We have previously described a pedigree in which affective disorder and Darier's disease cosegregate and, in an independent… 
1996
1996
Synergistic effect of interleukin-1 beta and tumor necrosis factor alpha on PGE2 production by articular chondrocytes does not involve PLA2 stimulation.
This study investigates the ways in which two proinflammatory cytokines, tumor necrosis factor alpha (TNF) and interleukin-1 beta… 
1994
1994
[Phospholipase A2 and premature membrane rupture].
The phospholipase A2 activity in young amniotic fluids: 1.782, was determined. In the term amniotic fluids, the activity was 10… 
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