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PKCbeta

National Institutes of Health

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protein kinase C activity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Ethanol Reduces GABAA α1 Subunit Receptor Surface Expression by a Protein Kinase Cγ-Dependent Mechanism in Cultured Cerebral Cortical Neurons
Prolonged ethanol exposure causes central nervous system hyperexcitability that involves a loss of GABAergic inhibition. We… 
2009
2009
Serine 649 Phosphorylation within the Protein Kinase C-Regulated Domain Down-Regulates CARMA1 Activity in Lymphocytes1
Phosphorylation of CARMA1 is a crucial event initiating the assembly of IκB kinase and JNK signaling complexes downstream of… 
2008
2008
Kinetic Analysis of the Interaction of the C1 Domain of Protein Kinase C with Lipid Membranes by Stopped-flow Spectroscopy*
The diacylglycerol (DG)/phorbol ester-dependent translocation of conventional protein kinase C (PKC) isozymes is mediated by the… 
Highly Cited
2004
Highly Cited
2004
Protein Kinase CβII Regulates Its Own Expression in Rat Intestinal Epithelial Cells and the Colonic Epithelium in Vivo*
Protein kinase C βII (PKCβII) is induced early during colon carcinogenesis. Transgenic mice expressing elevated PKCβII in the… 
Review
2002
Review
2002
Potential new medical therapies for diabetic retinopathy: protein kinase C inhibitors.
2001
2001
Follicle-stimulating hormone promotes the growth of human epithelial ovarian cancer cells through the protein kinase C-mediated system.
2001
2001
Cutting Edge: Protein Kinase Cβ Expression Is Critical for Export of IL-2 from T Cells1
Protein kinase C (PKC) plays an integral part in T cell activation and IL-2 secretion. We investigated the role of a particular… 
1999
1999
In L6 Skeletal Muscle Cells, Glucose Induces Cytosolic Translocation of Protein Kinase C-α and Trans-activates the Insulin Receptor Kinase*
In L6 skeletal muscle cells expressing human insulin receptors (L6hIR), exposure to 25 mm glucose for 3 min induced a rapid 3… 
Highly Cited
1998
Highly Cited
1998
Distinct PKC isoforms mediate the activation of cPLA2 and adenylyl cyclase by phorbol ester in RAW264.7 macrophages
The modulatory effects of protein kinase C (PKC) on the activation of cytosolic phospholipase A2 (cPLA2) and adenylyl cyclase (AC… 
1998
1998
Protein kinase C β modulates thrombin‐induced Ca2+ signaling and endothelial permeability increase
We investigated the function of the Ca2+‐dependent protein kinase C (PKC) β1 in the regulation of endothelial barrier property… 
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