PKCbeta

 
National Institutes of Health

Papers overview

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2010
2010
We investigated whether the diabetes-related PKCbeta activation affects VEGF expression through the mRNA-stabilizing human… (More)
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2009
2009
Endothelial activation is a central initiating event in atheroma formation. Evidence from our laboratory and others has… (More)
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2008
2008
Protein kinase C-betaII (PKCbetaII) is an important modulator of cellular stress responses. To test the hypothesis that PKCbetaII… (More)
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Highly Cited
2006
Highly Cited
2006
Syndecan-4 is a ubiquitously expressed transmembrane heparan sulphate proteoglycan acting in concert with integrins in the… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND Activation of vascular endothelial cells (ECs) plays an important role in atherogenesis and plaque instability… (More)
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Highly Cited
2005
Highly Cited
2005
PKC isoforms and CARMA1 play crucial roles in immunoreceptor-dependent NF-kappaB activation. We tested whether PKC-dependent… (More)
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2004
2004
We report herein synthesis of PKCbeta-selective inhibitors possessing the novel pharmacophore of anilino-monoindolylmaleimide… (More)
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2003
2003
The synthesis and structure-activity relationship (SAR) trends of a new class of N-(azacycloalkyl)bisindolylmaleimides 1, acyclic… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND The vasodilatory effect of insulin can be acute or increase with time from 1 to 7 hours, suggesting that insulin may… (More)
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Highly Cited
1997
Highly Cited
1997
Increased cardiovascular mortality occurs in diabetic patients with or without coronary artery disease and is attributed to the… (More)
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