PIN1 gene

Known as: DODO, DROSOPHILA, HOMOLOG OF, PIN1, peptidylprolyl cis/trans isomerase, NIMA-interacting 1 
This gene plays a role in the regulation of the post-phosphorylation conformation of protein substrates.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Alzheimer disease (AD) is characterized neuropathologically by intracellular neurofibrillary tangles (NFT) and of extracellular… (More)
  • table 2
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Phosphorylation of proteins on serine or threonine residues preceding proline (pSer/Thr-Pro) is a major regulatory mechanism in… (More)
  • figure 1
  • table 1
  • table 2
  • figure 3
  • table 3
Is this relevant?
Highly Cited
2003
Highly Cited
2003
The neuropathological hallmarks of Alzheimer's disease and other tauopathies include senile plaques and/or neurofibrillary… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2002
Highly Cited
2002
The tumour suppressor p53 is important in the cell decision to either arrest cell cycle progression or induce apoptosis in… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2002
Highly Cited
2002
p53 is activated in response to various genotoxic stresses resulting in cell cycle arrest or apoptosis. It is well documented… (More)
  • figure 1
  • figure 3
  • figure 2
  • figure 4
  • figure 1
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Phosphorylation on serines or threonines preceding proline (Ser/Thr-Pro) is a major signaling mechanism. The conformation of a… (More)
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Phosphorylation on a serine or threonine residue preceding proline (Ser/Thr-Pro) is a key regulatory mechanism, and the… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2000
Highly Cited
2000
The reversible protein phosphorylation on serine or threonine residues that precede proline (pSer/Thr-Pro) is a key signaling… (More)
Is this relevant?
Highly Cited
1999
Highly Cited
1999
One of the neuropathological hallmarks of Alzheimer's disease is the neurofibrillary tangle, which contains paired helical… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
The human rotamase or peptidyl-prolyl cis-trans isomerase Pin1 is a conserved mitotic regulator essential for the G2/M transition… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?