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PIK3R2 gene
Known as:
PIK3R2
, phosphoinositide-3-kinase regulatory subunit beta
, p85
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This gene is involved in the regulation of receptor tyrosine kinase activity.
National Institutes of Health
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Related topics
Related topics
7 relations
Apoptosis
PIK3R3 gene
Phosphorylation
Platelet Activation
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PIK3R2 wt Allele
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Candidate tumor suppressor gene IRF6 is involved in human breast cancer pathogenesis via modulating PI3K-regulatory subunit PIK3R2 expression
Hong-Fa Xu
,
Tie-jun Huang
,
+10 authors
Bi-Jun Huang
Cancer Management and Research
2019
Corpus ID: 196661426
Background/Aims: The tumor-suppressive functions of interferon regulatory factor 6 (IRF6) in some tumors have been preliminarily…
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2018
2018
Polymicrogyria in association with hypoglycemia points to mutation in the mTOR pathway.
C. Stutterd
,
G. McGillivray
,
+5 authors
R. Leventer
European Journal of Medical Genetics
2018
Corpus ID: 47003774
2018
2018
Ricolinostat (ACY-1215) suppresses proliferation and promotes apoptosis in esophageal squamous cell carcinoma via miR-30d/PI3K/AKT/mTOR and ERK pathways
Jin-lin Cao
,
W. Lv
,
+5 authors
Jian Hu
Cell Death and Disease
2018
Corpus ID: 256606478
Ricolinostat (ACY-1215), a first-in-class selective HDAC6 inhibitor, exhibits antitumor effects alone or in combination with…
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2016
2016
MicroRNA-126-3p suppresses cell proliferation by targeting PIK3R2 in Kaposi's sarcoma cells
Xiu-juan Wu
,
Zongfeng Zhao
,
Xiao-Jing Kang
,
Hong-juan Wang
,
Juan Zhao
,
X. Pu
OncoTarget
2016
Corpus ID: 15674574
Kaposi's sarcoma is a highly vascular tumor of lymphatic endothelial origin. Many deregulated miRNAs, including miR-126-3p, have…
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Review
2016
Review
2016
Genomic profiling and treatment of HER2+, ER+, PgR+ “triple positive” breast cancer: A case report and literature review
R. Schwab
,
M. Koehler
,
Siraj M. Ali
,
B. Murray
2016
Corpus ID: 78049278
2016
2016
Chasing Therapeutic Targets in Thymic Malignancies: Finding Needles in the Haystack to Frame a Comprehensive Canvas?
N. Girard
Journal of Thoracic Oncology
2016
Corpus ID: 31193880
2015
2015
Activated Phosphatidylinositol 3-Kinase/Akt Inhibits the Transition of Endothelial Progenitor Cells to Mesenchymal Cells by Regulating the Forkhead Box Subgroup O-3a Signaling
Zongqi Zhang
,
Tiantian Zhang
,
+4 authors
Changqian Wang
Cellular Physiology and Biochemistry
2015
Corpus ID: 24230679
Background and Aims: Endothelial progenitor cells (EPCs) differentiate into mature endothelial cells and may thus be candidates…
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2015
2015
MicroRNA-126 targeting PIK 3 R 2 promotes rheumatoid arthritis synovial fibroblasts proliferation and resistance to apoptosis by regulating PI 3 K / AKT pathway Running title : miR-126 targeting PIK…
Jie Gao
,
Xiaoli Zhou
,
R. Kong
,
Lianmei Ji
,
Ling-ling He
,
Dongbao Zhao
2015
Corpus ID: 207843377
2015
2015
Epilepsy treatment: precision medicine at a crossroads
D. Lindhout
Lancet Neurology
2015
Corpus ID: 26210009
2010
2010
Andes Virus Regulation of Cellular MicroRNAs Contributes to Hantavirus-Induced Endothelial Cell Permeability
Timothy Pepini
,
E. Gorbunova
,
I. Gavrilovskaya
,
Jonathan E Mackow
,
E. Mackow
Journal of Virology
2010
Corpus ID: 24548857
ABSTRACT Hantaviruses infect human endothelial cells (ECs) and cause two diseases marked by vascular permeability defects…
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