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PIAS3 Gene

Known as: Protein Inhibitor of Activated STAT, 3 Gene, PROTEIN INHIBITOR OF ACTIVATED STAT3, FLJ14651 
This gene is involved in transcriptional coregulation and protein degradation.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Background:MicroRNA (miRNA, miR)-18a is a member of the miR-17–92 cluster, an important locus that is markedly overexpressed in… Expand
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Highly Cited
2010
Highly Cited
2010
TRIM8 is a member of the protein family defined by the presence of a common domain structure composed of a tripartite motif: a… Expand
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Highly Cited
2008
Highly Cited
2008
Purpose: STATs activate transcription in response to numerous cytokines, controlling proliferation, gene expression, and… Expand
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Highly Cited
2004
Highly Cited
2004
STAT3 mediated signaling pathways can be inhibited by PIAS3 (protein inhibitor of activated STAT3), which was recently found to… Expand
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Highly Cited
2004
Highly Cited
2004
Nuclear factor-κB (NF-κB) is a transcription factor critical for key cellular processes, including immune response, apoptosis… Expand
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Highly Cited
2003
Highly Cited
2003
Smad proteins play pivotal roles in mediating the transforming growth factor β (TGF-β) transcriptional responses. We show in this… Expand
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Highly Cited
2002
Highly Cited
2002
Interferon regulatory factor-1 (IRF-1) is a transcriptional activator that is involved in interferon response, regulation of cell… Expand
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Highly Cited
2001
Highly Cited
2001
Estrogen receptors (ERs)1highly expressed by multiple myeloma (MM) cells and stimulation of estrogenic ligands leads to cell… Expand
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Highly Cited
2000
Highly Cited
2000
STAT factors act as signal transducers of cytokine receptors and transcriptionally activate specific target genes. The recently… Expand
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Highly Cited
1997
Highly Cited
1997
The signal transducer and activator of transcription-3 (Stat3) protein is activated by the interleukin 6 (IL-6) family of… Expand
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