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PIAS3 Gene

Known as: Protein Inhibitor of Activated STAT, 3 Gene, PROTEIN INHIBITOR OF ACTIVATED STAT3, FLJ14651 
This gene is involved in transcriptional coregulation and protein degradation.
National Institutes of Health

Related topics

Related topics

3 relations
PIAS3 protein, humanSignal TransductionTranscriptional Regulation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Modification of DBC1 by SUMO2/3 is crucial for p53-mediated apoptosis in response to DNA damage
DBC1 is a major inhibitor of SIRT1, which plays critical roles in the control of diverse cellular processes, including stress… 
2013
2013
Suppressed Th17 Levels Correlate with Elevated PIAS3, SHP2, and SOCS3 Expression in CD4 T Cells during Acute Simian Immunodeficiency Virus Infection
ABSTRACT T helper 17 (Th17) cells play an important role in mucosal immune homeostasis and maintaining the integrity of the… 
2010
2010
Sumoylation of Vimentin354 Is Associated with PIAS3 Inhibition of Glioma Cell Migration
The invasive phenotype of glioblastoma multiforme (GBM) is a hallmark of malignant process, yet the molecular mechanisms that… 
2010
2010
Polymorphisms in the UBC9 and PIAS3 genes of the SUMO-conjugating system and breast cancer risk
SUMOylation consists in the covalent conjugation of small ubiquitin-related modifiers to target proteins. SUMOylation… 
2010
2010
N-terminal truncation of Stat5a/b circumvents PIAS3-mediated transcriptional inhibition of Stat5 in prostate cancer cells.
2009
2009
The Association and Nuclear Translocation of the PIAS3-STAT3 Complex Is Ligand and Time Dependent
The epidermal growth factor (EGF) receptor activation of downstream signal transducers and activators of transcription 3 (STAT3… 
2006
2006
Identifying a common molecular mechanism for inhibition of MITF and STAT3 by PIAS3.
Protein inhibitor of activated STAT3 (PIAS3) functions in vivo as a key molecule in suppressing the transcriptional activity of… 
Highly Cited
2002
Highly Cited
2002
PIAS3 induces SUMO‐1 modification and transcriptional repression of IRF‐1
Highly Cited
2002
Highly Cited
2002
A New Role for the STAT3 Inhibitor, PIAS3
In vitro and in vivoevidence suggest that microphthalmia transcription factor (MITF) plays a key regulatory role in tissue… 
2002
2002
PIAS3 (protein inhibitor of activated STAT‐3) modulates the transcriptional activation mediated by the nuclear receptor coactivator TIF2
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