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PIAS1 gene

Known as: PIAS1, GU-BINDING PROTEIN, protein inhibitor of activated STAT 1 
This gene is involved in both signal transduction and the sumoylation of proteins.
National Institutes of Health

Related topics

Related topics

7 relations
E3 SUMO-Protein Ligase PIAS1Interferon Signaling ProcessPIAS1 protein, humanPIAS2 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Molecular and Cellular Pathobiology The SUMOE 3-ligase PIAS 1 Regulates the Tumor Suppressor PML and Its Oncogenic Counterpart PML-RARA
The ubiquitin-like SUMO proteins covalently modify protein substrates and regulate their functional properties. In a broad… 
2011
2011
mRNA expression of BRCA1, PIAS1, and PIAS4 and survival after second-line docetaxel in advanced gastric cancer.
Breast cancer susceptibility gene 1 (BRCA1) has a central role in chemotherapy-induced DNA damage response. The protein inhibitor… 
2011
2011
Glucocorticoid Causes Iron Accumulation in Liver by Up-Regulating Expression of Iron Regulatory Protein 1 Gene Through GR and STAT5
Iron regulatory protein-1 (IRP-1) is a central factor in the regulation of iron metabolism. Stress causes elevated glucocorticoid… 
2007
2007
Perforator stroke after elective stenting of symptomatic intracranial stenosis. Authors' reply
2005
2005
Nuclear Receptors as Negative Modulators of STAT3 in Multiple Myeloma
Multiple myeloma (MM) remains largely incurable despite conventional and high-dose therapies. Therefore, novel biologically based… 
2005
2005
[Negative regulation of the JAK/STAT: pathway implication in tumorigenesis].
Cytokines, hormones or growth factors induce a variety of biological responses including proliferation, differentiation and… 
Review
2004
Review
2004
Intracellular Proteins and Mechanisms Involved in the Control of gp130/JAK/STAT Cytokine Signaling
Cytokines regulate many cellular responses such as proliferation, differentiation and survival and play regulatory roles in… 
2004
2004
Repression of the Transactivating Capacity of the Oncoprotein PLAG1 by SUMOylation*
Human pleomorphic adenoma gene 1 (PLAG1), a developmentally regulated proto-oncogene, is consistently rearranged and… 
Highly Cited
2002
Highly Cited
2002
Protein Inhibitors of Activated STAT Resemble Scaffold Attachment Factors and Function as Interacting Nuclear Receptor Coregulators*
Protein inhibitor of activated STAT1 (PIAS1) functions as a nuclear receptor coregulator and is expressed in several cell types… 
Highly Cited
2002
Highly Cited
2002
Androgen Receptor-interacting Protein 3 and Other PIAS Proteins Cooperate with Glucocorticoid Receptor-interacting Protein 1 in Steroid Receptor-dependent Signaling*
Androgen receptor (AR)-interacting protein 3 (ARIP3/PIASxα) is a coregulator capable of modulating transcriptional activity of… 
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