PF-562,271

 

Topic mentions per year

Topic mentions per year

2008-2016
012320082016

Papers overview

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2015
2015
Glioblastoma is one of the most aggressive and fatal brain cancers due to the highly invasive nature of glioma cells. Microglia… (More)
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2014
2014
Ovarian clear cell carcinoma (OCCC) displays a higher resistance to first line chemotherapy, requiring the development of new… (More)
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2013
2013
The focal adhesion kinase inhibitor, PF-562,271, is currently in clinical development for cancer, however it is not known how PF… (More)
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2012
2012
OBJECTIVE Enhanced adhesive signaling, including activation of focal adhesion kinase (FAK), is a hallmark of fibroblasts from… (More)
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2012
2012
Focal adhesion kinase (FAK) is upregulated in several epithelial tumours and there has been considerable interest in developing… (More)
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2011
2011
Current therapies for pancreatic ductal adenocarcinoma (PDA) target individual tumor cells. Focal adhesion kinase (FAK) is… (More)
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2010
2010
Focal adhesion kinase (FAK) is essential in regulating integrin signaling pathways responsible for cell survival and… (More)
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2009
2009
EXPERIMENTAL DESIGN To investigate the antitumor effect of sunitinib and FAK/Pyk2 tyrosine kinase inhibitor (PF-562,271… (More)
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Highly Cited
2008
Highly Cited
2008
Cancer cells are characterized by the ability to grow in an anchorage-independent manner. The activity of the nonreceptor… (More)
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2008
2008
BACKGROUND Lytic bone metastases occur frequently in cancer patients and present major clinical issues including lack of… (More)
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