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PF-00562271

National Institutes of Health

Papers overview

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2019
2019
In this issue of Targeted Oncology, the BI 853520 investigators present three complementary studies of BI 853520 that investigate… 
2017
2017
Background/Aims: Istaroxime is a validated inotropic Na+/K+ ATPase inhibitor currently in development for the treatment of… 
2013
2013
Docetaxel remains the standard-of-care for men diagnosed with metastatic castrate-resistant prostate cancer (CRPC). However, only… 
Highly Cited
2012
Highly Cited
2012
PURPOSE PF-00562271 is a novel inhibitor of focal adhesion kinase (FAK). The objectives of this study were to identify the… 
2010
2010
3028 Background: FAK is a non-receptor tyrosine kinase that transduces signaling from integrins and growth factor receptors to… 
2008
2008
3534 Background: FAK transduces signaling from integrins and growth factors to modulate tumor cell invasion, proliferation and…