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PEN-2 protein, C elegans

National Institutes of Health

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Caenorhabditis elegans ProteinsMembrane Proteins

Papers overview

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2007
2007
Abeta42 overproduction associated with structural changes in the catalytic pore of gamma-secretase: common effects of Pen-2 N-terminal elongation and fenofibrate.
gamma-Secretase is an atypical aspartyl protease that cleaves amyloid beta-precursor protein to generate Abeta peptides that are… 
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