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PDIA6 gene

Known as: ERP5, ENDOPLASMIC RETICULUM PROTEIN 5, protein disulfide isomerase family A member 6 
This gene plays a role in protein folding and platelet aggregation.
National Institutes of Health

Related topics

Related topics

5 relations
PDIA6 wt AllelePlatelet aggregationProtein Disulfide-Isomerase A6, HumanProtein Disulfide-Isomerases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2019
Highly Cited
2019
PDIA6 modulates apoptosis and autophagy of non-small cell lung cancer cells via the MAP4K1/JNK signaling pathway
Highly Cited
2016
Highly Cited
2016
PDIA6 regulates insulin secretion by selectively inhibiting the RIDD activity of IRE1
Protein disulfide isomerase A6 (PDIA6) interacts with protein kinase RNA‐like endoplasmic reticulum kinase (PERK) and inositol… 
Highly Cited
2016
Highly Cited
2016
Heat Shock Protein member A2 forms a stable complex with angiotensin converting enzyme and protein disulfide isomerase A6 in human spermatozoa.
STUDY HYPOTHESIS Given the importance of the chaperone Heat Shock Protein A2 (HSPA2) in the regulation of male fertility, this… 
Highly Cited
2015
Highly Cited
2015
Crocin and Quercetin protect HCT116 and HEK293 cells from Zearalenone-induced apoptosis by reducing endoplasmic reticulum stress
Mycotoxins are considered to be significant contaminants of food and animal feed. Zearalenone (ZEN) is a non-steroidal estrogenic… 
Highly Cited
2014
Highly Cited
2014
Protein disulfide isomerase A6 controls the decay of IRE1α signaling via disulfide-dependent association.
Highly Cited
2014
Highly Cited
2014
The protein disulfide isomerases PDIA4 and PDIA6 mediate resistance to cisplatin-induced cell death in lung adenocarcinoma
Intrinsic and acquired chemoresistance are frequent causes of cancer eradication failure. Thus, long-term cis… 
Highly Cited
2012
Highly Cited
2012
Protein disulfide isomerase-associated 6 is an ATF6-inducible ER stress response protein that protects cardiac myocytes from ischemia/reperfusion-mediated cell death.
2009
2009
Proteins upregulated by mild and severe hypoxia in squamous cell carcinomas in vitro identified by proteomics.
Highly Cited
2009
Highly Cited
2009
Crystal structure and functional analysis of the protein disulfide isomerase-related protein ERp29.
2008
2008
A Point Mutation in Translation Initiation Factor 2B Leads to a Continuous Hyper Stress State in Oligodendroglial-Derived Cells
Background Mutations in eukaryotic translation initiation factor 2B (eIF2B) cause Childhood Ataxia with CNS Hypomyelination (CACH… 
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