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PDGFRB wt Allele

Known as: Platelet-Derived Growth Factor Receptor, Beta Polypeptide wt Allele, JTK12, PDGFR Beta 
Human PDGFRB wild-type allele is located within 5q31-q32 and is approximately 42 kb in length. This allele, which encodes beta platelet-derived… 
National Institutes of Health

Related topics

Related topics

12 relations
5q31-q32Cell ProliferationHomo sapiensLigand Binding

Broader (1)

PDGFRB gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Systematic use of fluorescence in‐situ hybridisation and clinicopathological features in the screening of PDGFRB rearrangements of patients with myeloid/lymphoid neoplasms
Rearrangement of the platelet‐derived growth factor receptor B (PDGFRB) gene defines a unique group of myeloid/lymphoid neoplasms… 
2019
2019
Myopericytomatosis of the Foot: a Case Report Including Molecular Identification of a PDGFRB Mutation
This case report is about myopericytomatosis, a recently described rare tumor entity with only a dozen cases found in PubMed… 
2017
2017
SATB1 plays an oncogenic role in esophageal cancer by up-regulation of FN1 and PDGFRB
Esophageal cancer is a highly aggressive malignancy with very poor overall prognosis. Given the strong clinical relevance of… 
2016
2016
Ph-like ALL-related novel fusion kinase ATF7IP-PDGFRB exhibits high sensitivity to tyrosine kinase inhibitors in murine cells.
Highly Cited
2013
Highly Cited
2013
Successful tyrosine kinase inhibitor therapy in a refractory B-cell precursor acute lymphoblastic leukemia with EBF1-PDGFRB fusion
The advent of tyrosine kinase inhibitors (TKI) has profoundly changed the current therapeutic approach in some hematologic… 
2013
2013
Small molecule-based chemotherapeutic approach in p16-positive and -negative HNSCC in vitro.
BACKGROUND Incidence of oropharyngeal head and neck squamous cell carcinoma (HNSCC) induced by the human papilloma virus (HPV) is… 
2012
2012
Incidence and clinical characteristics of myeloproliferative neoplasms displaying a PDGFRB rearrangement
The myeloproliferative neoplasms displaying a PDGFRB rearrangement are rare diseases derived from a haematopoietic stem cell. The… 
2011
2011
Time-specific blockade of PDGFR with Imatinib (Glivec®) causes cataract and disruption of lens fiber cells in neonatal mice
This study aimed at investigating the response of lens epithelial cells in postnatal mice to Imatinib (Glivec®, a potent… 
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