PDGFA gene

Known as: PDGF-A, PDGF A-chain, PDGFA 
This gene plays a role in cellular growth and proliferation. It is also involved in intercellular signaling.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1986-2018
0102019862018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Cholangiocarcinoma (CCA) is a crucial health problem in northeastern part of Thailand, which is caused by a combination of… (More)
Is this relevant?
2009
2009
Background:Malignant gliomas are the most prevalent type of primary brain tumours but the therapeutic armamentarium for these… (More)
  • table 1
  • figure 1
  • table 2
  • figure 2
  • table 3
Is this relevant?
2008
2008
PURPOSE Pancreatic cancer still has one of the worst prognoses in gastrointestinal cancers with a 5-year survival rate of 5… (More)
Is this relevant?
2008
2008
PURPOSE The majority of gastrointestinal stromal tumors (GIST) can be cured by surgery alone, but relapse occurs in 20% to 40% of… (More)
Is this relevant?
1997
1997
Platelet-derived growth factor (PDGF) A-chain is expressed by vascular smooth muscle cells (SMC) in a variety of pathological… (More)
Is this relevant?
1992
1992
The PDGFs are a family of molecules assembled as disulfide-bonded homo- and heterodimers from two distinct but highly homologous… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • table III
Is this relevant?
1992
1992
The Wilms' tumor locus on chromosome 11p13 contains a tumor suppressor gene, wt1, which encodes a DNA binding protein (WT1) with… (More)
Is this relevant?
1992
1992
The human PDGFA gene has been mapped previously to two different sites on chromosome 7 (7p21----p22 and 7q11.2----q21.1). Using… (More)
Is this relevant?
1991
1991
Platelet-derived growth factor (PDGF) may be a critical factor in the temporal differentiation of glial elements in the mammalian… (More)
Is this relevant?
Highly Cited
1989
Highly Cited
1989
Both interleukin-1 (IL-1) and platelet-derived growth factor (PDGF) induce proliferation of cultured fibroblasts and smooth… (More)
Is this relevant?