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PDGF Signaling Pathway

Platelet Derived Growth Factor (PDGF) plays a critical role in cellular proliferation and development. The biologically active form is a dimer formed… 
National Institutes of Health

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CSNK2A1 wt AlleleELK1 wt AlleleHRAS wt AlleleJAK1 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
High-Throughput Sequencing of Putative Novel microRNAs in Rhesus Monkey Peripheral Blood Mononuclear Cells following EV71 and CA16 Infection
Objectives: Enterovirus 71 (EV71) and Coxsackievirus A16 (CA16) remain the major pathogens in hand, foot, and mouth disease (HFMD… 
2017
2017
Genetic variants of PDGF signaling pathway genes predict cutaneous melanoma survival
To investigate whether genetic variants of platelet-derived growth factor (PDGF) signaling pathway genes are associated with… 
2016
2016
Xanthohumol inhibits PDGF-BB-induced vascular smooth muscle cell proliferation and migration through suppression of PDGF signaling pathway
Proliferation and migration of vascular smooth muscle cells (VSMCs) contribute to the development of atherosclerosis. Xanthohumol… 
2015
2015
Targeting the VEGF and PDGF signaling pathway in glioblastoma treatment.
Growth factor receptors dysfunction has previously been correlated with glioma cell proliferation, ability to evade apoptosis… 
2013
2013
Targeting the PDGF signaling pathway in tumor
Platelet-derived growth factor (PDGF) isoforms and PDGF receptors have important functions in the regulation of growth and… 
2007
2007
Elucidating progesterone effects in breast cancer: Cross talk with PDGF signaling pathway in smooth muscle cell
Several studies indicate that progesterone exerts relevant effects in breast tissue. However, the exact role of this steroid in… 
Highly Cited
2006
Highly Cited
2006
Curcumin Inhibits Platelet-Derived Growth Factor–Stimulated Vascular Smooth Muscle Cell Function and Injury-Induced Neointima Formation
Objective—Vascular smooth muscle cell (VSMC) migration, proliferation, and collagen synthesis are key events involved in the… 
Highly Cited
2003
Highly Cited
2003
The Antioxidant (–)-Epigallocatechin-3-gallate Inhibits Rat Hepatic Stellate Cell Proliferation in Vitro by Blocking the Tyrosine Phosphorylation and Reducing the Gene Expression of Platelet-derived…
During hepatic fibrogenesis, quiescent hepatic stellate cells (HSC) become active and trans-differentiate into myofibroblast-like… 
1995
1995
An intact PDGF signaling pathway is required for efficient growth transformation of mouse C127 cells by the bovine papillomavirus E5 protein.
The bovine papillomavirus type 1 (BPV) E5 protein is a 44 amino acid, membrane-associated protein that induces growth… 
1993
1993
Platelet derived growth factor (PDGF), androgens and inflammation: possible etiologic factors in the development of prostatic hyperplasia.
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