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PDGF Signaling Pathway

Platelet Derived Growth Factor (PDGF) plays a critical role in cellular proliferation and development. The biologically active form is a dimer formed… 
National Institutes of Health

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CSNK2A1 wt AlleleELK1 wt AlleleHRAS wt AlleleJAK1 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Xanthohumol inhibits PDGF-BB-induced vascular smooth muscle cell proliferation and migration through suppression of PDGF signaling pathway
Proliferation and migration of vascular smooth muscle cells (VSMCs) contribute to the development of atherosclerosis. Xanthohumol… 
2016
2016
Une approche moléculaire pour mieux comprendre l'infertilité chez la vache laitière
Over the last fifty or more years, genetic selection has been employed to improve milk production in dairy cattle. This selection… 
Review
2011
Review
2011
Platelet-derived growth factor (PDGF) signaling: Detailed mechanistic insights
It is worth mentioning that large body of experimental evidence interconnects the deregulation of specific platelet-derived… 
2011
2011
P4-01-01: Preclinical and Clinical Studies of Estrogen Deprivation Support the PDGF/Abl Pathway as a Novel Therapeutic Target for Overcoming Resistance.
Aim: To determine the relevance of PDGF/Abl signaling pathway as a therapeutic target in endocrine resistance in vitro and in… 
2010
2010
MTSS 1 : a multifunctional protein and its role in cancer invasion and metastasis
1. Abstract 2. Introduction 3. Cytoskeletal regulation in cancer cell migration 3.1 Membrane protrusions formed by migrating… 
2006
2006
Exploration of gene expression networks that regulate cell-cell interaction during angiogenesis by transcript profiling in an in vitro angiogenesis co-culture model
139 Angiogenesis is a complex biological process involving cell-cell interactions between the vessel forming endothelial cells… 
2005
2005
K 252 a Inhibits Proliferation of Glioma Cells by Blocking Platelet-. derived Growth Factor Signal Transduction 1
Growth factors are known to regulate giloma proliferation. The glioma cell lines U87 and T9SG were examined for evidence of an… 
2001
2001
p 160 Bcr Mediates Platelet-Derived Growth Factor Activation of Extracellular Signal – Regulated Kinase in Vascular Smooth Muscle Cells
Background—The human Bcr gene was originally identified by its presence in the chimeric Bcr/Abl oncogene, which is causative for… 
1991
1991
BALB/c-3T3 fibroblasts resistant to growth inhibition by beta interferon exhibit aberrant platelet-derived growth factor, epidermal growth factor, and fibroblast growth factor signal transduction
Several lines of evidence now exist to suggest an interaction between the platelet-derived growth factor (PDGF) growth… 
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