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PDE9A gene

Known as: PDE9A, PHOSPHODIESTERASE 9A, Phosphodiesterase 9A Gene 
This gene plays a role in the metabolism of cyclic nucleotide monophosphates.
National Institutes of Health

Related topics

Related topics

3 relations
HydrolysisNucleotide MetabolismSignal Transduction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Discovering Biomarkers and Pathways Shared by Alzheimer’s Disease and Ischemic Stroke to Identify Novel Therapeutic Targets
Background and objectives: Alzheimer’s disease (AD) is a progressive neurodegenerative disease that results in severe dementia… 
2017
2017
Effects of diet and arginine treatment during the luteal phase on ovarian NO/PGC-1α signaling in ewes.
2016
2016
cUMP hydrolysis by PDE3A
As previously reported, the cardiac phosphodiesterase PDE3A hydrolyzes cUMP. Moreover, cUMP-degrading activity was detected in… 
2015
2015
Molecular dynamics-based discovery of novel phosphodiesterase-9A inhibitors with non-pyrazolopyrimidinone scaffolds.
Phosphodiesterase-9A (PDE9A) is a promising therapeutic target for the treatment of diabetes and Alzheimer's disease (AD). The… 
Review
2014
Review
2014
The Use of PDE10A and PDE9 Inhibitors for Treating Schizophrenia
Schizophrenia (Scz) is a chronic and debilitating neurological disorder that afflicts approximately 1% of the general population… 
2013
2013
Phosphodiesterase-9 (PDE9) inhibition with BAY 73-6691 increases corpus cavernosum relaxations mediated by nitric oxide–cyclic GMP pathway in mice
Phosphodiesterase-9 (PDE9) specifically hydrolyzes cyclic GMP, and was detected in human corpus cavernosum. However, no previous… 
2012
2012
Identification of phosphodiesterase 9A as a cyclic guanosine monophosphate-specific phosphodiesterase in germinal vesicle oocytes: a proposed role in the resumption of meiosis.
2011
2011
Alterations in cyclic nucleotide phosphodiesterase activities in omental and subcutaneous adipose tissues in human obesity
Objective:To elucidate the activity and expression of cyclic nucleotide phosphodiesterase (PDE) families in omental (OM) and… 
2011
2011
Identification of New Signaling Components in the Sensory Epithelium of Human Saccule
Objective: To locate components and target proteins of relevance for the cAMP and cGMP signaling networks including cAMP and cGMP… 
2008
2008
Noncoding RNA and DNA as biomarkers: toward an epigenetic fetal barcode for use in maternal plasma.
The human genome contains a large layer of hidden biological information that is not accessible by proteomic or metabolic methods… 
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