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PDE8B gene

Known as: PDE8B, PHOSPHODIESTERASE 8B, Phosphodiesterase 8B Gene 
This gene plays a role in the metabolism of cyclic AMP.
National Institutes of Health

Related topics

Related topics

3 relations
HydrolysisNucleotide MetabolismSignal Transduction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Phosphodiesterase 8B Polymorphism rs4704397 Is Associated with Infertility in Subclinical Hypothyroid Females: A Case-Control Study
Background Subclinical hypothyroidism (SCH) remains largely unnoticed as a major cause of infertility due to asymptomatic… 
2017
2017
Association of established hypothyroidism-associated genetic variants with Hashimoto’s thyroiditis
PurposeHashimoto’s thyroiditis (HT) as a chronic autoimmune disease of the thyroid gland is the most common cause of… 
Review
2015
Review
2015
Phosphodiesterase 8B and cyclic AMP signaling in the adrenal cortex
Bilateral adrenocortical hyperplasia (BAH) in humans and mice has been recently linked to phosphodiesterase (PDE) 8B (PDE8B) and… 
2015
2015
Genetic association study of phosphodiesterase 8B gene with subclinical hypothyroidism in pregnant women
Abstract Objective: To explore whether phosphodiesterase 8B (PDE8B) gene is involved in the etiology of subclinical… 
2014
2014
E pluribus unum? The main protein kinase A catalytic subunit (PRKACA), a likely oncogene, and cortisol-producing tumors.
Evidence has been accumulating for years that increased cAMP signaling (Figure 1) is the culprit behind the development of most… 
2014
2014
Frequency and effect on serum TSH of phosphodiesterase 8B (PDE8B) gene polymorphisms in patients with sporadic nonautoimmune subclinical hypothyroidism
BackgroundNonautoimmune subclinical hypothyroidism (NSH) is characterized by elevated serum TSH in presence of normal thyroid… 
2012
2012
Role of phosphodiesterases in the shaping of sub-plasma-membrane cAMP oscillations and pulsatile insulin secretion
Summary Specificity and versatility in cyclic AMP (cAMP) signalling are governed by the spatial localisation and temporal… 
2012
2012
Discovery of triazolopyrimidine-based PDE8B inhibitors: exceptionally ligand-efficient and lipophilic ligand-efficient compounds for the treatment of diabetes.
2012
2012
[Association analysis of PDE8B gene polymorphisms with the susceptibility to Hyperthyroxinemia in Chinese Han population].
OBJECTIVE To explore the correlations of the polymorphisms of phosphodiesterase 8B (PDE8B) gene with Hyperthyroxinemia in Chinese… 
2010
2010
The effect of genetic variation in PDE8B and DIO1 on thyroid hormone levels
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