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PDE5A gene

Known as: PDE5A, PHOSPHODIESTERASE 5A, Phosphodiesterase 5A, cGMP-Specific Gene 
This gene plays a role in signaling.
National Institutes of Health

Related topics

Related topics

4 relations
Cyclic Nucleotide Phosphodiesterases, Type 5HydrolysisPDE5A protein, humanSignal Transduction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
The role of PDE5a in oocyte maturation of zebrafish.
2019
2019
Discovery of two novel hetero-tricyclic lead scaffolds as PDE5A inhibitor: virtual screening, molecular docking and pharmacophore modeling approach
Abstract Phosphodiesterase 5A enzyme has been the upcoming and promising target in hypertension management. In this research… 
2017
2017
Effects of diet and arginine treatment during the luteal phase on ovarian NO/PGC-1α signaling in ewes.
2012
2012
A non-brain penetrant PDE5A inhibitor improves functional recovery after stroke in rats.
PURPOSE Phosphodiesterase 5A (PDE5A) inhibitors improve functional recovery in experimental models of stroke in rats when… 
2012
2012
Isolation and Characterization of Smooth Muscle Cells from Rat Corpus Cavernosum Tissue for the Study of Erectile Dysfunction
Purpose Primary culture of the cavernous smooth muscle cells from corpus cavernous tissues is known to be difficult, mainly… 
Review
2011
Review
2011
Phosphodiesterases and cardiac cGMP: evolving roles and controversies.
Review
2009
Review
2009
Phosphodiesterase type 5 regulation in the penile corpora cavernosa.
INTRODUCTION Penile detumescence depends on the hydrolysis of cyclic guanosine monophosphate (cGMP) by phosphodiesterase type 5… 
2007
2007
Expression and activity of cAMP phosphodiesterase isoforms in pulmonary artery smooth muscle cells from patients with pulmonary hypertension : role for PDE 1
Murray F, Patel HH, Suda RY, Zhang S, Thistlethwaite PA, Yuan JX, Insel PA. Expression and activity of cAMP phosphodiesterase… 
2006
2006
Phosphodiesterase 3 and 5 and cyclic nucleotide-gated ion channel expression in rat trigeminovascular system
2003
2003
Modeling and mutational analysis of the GAF domain of the cGMP‐binding, cGMP‐specific phosphodiesterase, PDE5
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