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PDE5A gene

Known as: PDE5A, PHOSPHODIESTERASE 5A, Phosphodiesterase 5A, cGMP-Specific Gene 
This gene plays a role in signaling.
National Institutes of Health

Related topics

Related topics

4 relations
Cyclic Nucleotide Phosphodiesterases, Type 5HydrolysisPDE5A protein, humanSignal Transduction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
The role of PDE5a in oocyte maturation of zebrafish.
2017
2017
Distinct phosphodiesterase 5A-containing compartments allow selective regulation of cGMP-dependent signalling in human arterial smooth muscle cells.
2015
2015
Expression and distribution of phosphodiesterase isoenzymes in the human male urethra.
2014
2014
Sildenafil may elevate melanoma risk
Li et al. have reported in JAMA Internal Medicine that sildenafil (Viagra) may be associated with melanoma risk (1). Sildenafil… 
2012
2012
Isolation and Characterization of Smooth Muscle Cells from Rat Corpus Cavernosum Tissue for the Study of Erectile Dysfunction
Purpose Primary culture of the cavernous smooth muscle cells from corpus cavernous tissues is known to be difficult, mainly… 
2010
2010
Phosphodiesterase-5 gene (PDE5A) polymorphisms are associated with progression of childhood IgA nephropathy
The phosphodiesterase-5 (PDE-5) gene is highly specific to cyclic GMP (cGMP) and several experimental studies have shown that the… 
Review
2010
Review
2010
ReviewAmelioration of Penile Fibrosis : Myth or Reality
Several changes have been reported to occur in the cavernosal tissue and tunica albuginea with aging. The atherosclerosis of the… 
2007
2007
Expression and activity of cAMP phosphodiesterase isoforms in pulmonary artery smooth muscle cells from patients with pulmonary hypertension : role for PDE 1
Murray F, Patel HH, Suda RY, Zhang S, Thistlethwaite PA, Yuan JX, Insel PA. Expression and activity of cAMP phosphodiesterase… 
2005
2005
Role of PDE5a in cardiac stress response
PDE5a is a cGMP-selective phosphodiesterase that has been known to play a particularly important role in cGMP regulation within… 
2000
2000
The human phosphodiesterase PDE10A gene genomic organization and evolutionary relatedness with other PDEs containing GAF domains.
PDE10A is a cyclic nucleotide phosphodiesterase (PDE) exhibiting properties of a cAMP PDE and a cAMP-inhibited cGMP PDE. The… 
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