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Cyclic Nucleotide Phosphodiesterases, Type 5

Known as: Phosphodiesterase-5, Cyclic Nucleotide Phosphodiesterases, Type 5 [Chemical/Ingredient], Phosphodiesterases, PDE5 
A cyclic nucleotide phosphodiesterase subfamily that is highly specific for CYCLIC GMP. It is found predominantly in vascular tissue and plays an… 
National Institutes of Health

Related topics

Related topics

9 relations
In BloodPDE5A geneProcess of secretionaspects of radiation effects

Narrower (2)

PDE5A protein, humanPde5a protein, mouse

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
Shifting Patterns of Prescription Opioid and Heroin Abuse in the United States.
This analysis of data from surveys of patients with opioid dependence who were entering treatment programs in the United States… 
Review
2013
Review
2013
Systematic review of combination drug therapy for non-neurogenic male lower urinary tract symptoms.
Review
2010
Review
2010
Pharmacotherapy in pulmonary arterial hypertension: a systematic review and meta-analysis
BackgroundPrevious meta-analyses of treatments for pulmonary arterial hypertension (PAH) have not shown mortality benefit from… 
Highly Cited
2009
Highly Cited
2009
Modulators of arginine metabolism support cancer immunosurveillance
BackgroundTumor-associated accrual of myeloid derived suppressor cells (MDSC) in the blood, lymphoid organs and tumor tissues may… 
Highly Cited
2009
Highly Cited
2009
Erectile dysfunction after external beam radiotherapy for prostate cancer.
Highly Cited
2008
Highly Cited
2008
Compartmentation and compartment-specific regulation of PDE5 by protein kinase G allows selective cGMP-mediated regulation of platelet functions
It is generally accepted that nitric oxide (NO) donors, such as sodium nitroprusside (SNP), or phosphodiesterase 5 (PDE5… 
Review
2007
Review
2007
Interventions for sexual dysfunction following treatments for cancer.
BACKGROUND The proportion of people living with and surviving cancer is growing. This has led to increased awareness of the… 
Highly Cited
2006
Highly Cited
2006
Accurate mass measurement using Fourier transform ion cyclotron resonance mass spectrometry for structure elucidation of designer drug analogs of tadalafil, vardenafil and sildenafil in herbal and…
Phosphodiesterase type 5 (PDE-5) inhibitors are a class of drugs used primarily in the treatment of erectile dysfunction. The… 
Highly Cited
2006
Highly Cited
2006
Use of liquid chromatography-mass spectrometry and a hydrolytic technique for the detection and structure elucidation of a novel synthetic vardenafil designer drug added illegally to a "natural…
Review
2000
Review
2000
Cardiovascular risk and sildenafil.
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