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PDE4B gene

Known as: phosphodiesterase E4 dunce homolog (Drosophila), phosphodiesterase 4B, DUNCE-LIKE PHOSPHODIESTERASE E4, FORMERLY 
This gene plays a role in the metabolism of cyclic AMP.
National Institutes of Health

Related topics

Related topics

4 relations
HydrolysisPDE4B protein, humanSignal Transductionphosphodiesterase 4B

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Comparative effects of diet and carcinogen on microRNA expression in the stem cell niche of the mouse colonic crypt.
2015
2015
MicroRNA-124 regulates glucocorticoid sensitivity by targeting phosphodiesterase 4B in diffuse large B cell lymphoma.
2013
2013
Synthesis and biological evaluation of 5-carbamoyl-2-phenylpyrimidine derivatives as novel and potent PDE4 inhibitors.
2012
2012
Isolation and Characterization of Smooth Muscle Cells from Rat Corpus Cavernosum Tissue for the Study of Erectile Dysfunction
Purpose Primary culture of the cavernous smooth muscle cells from corpus cavernous tissues is known to be difficult, mainly… 
Highly Cited
2006
Highly Cited
2006
Regulation of phosphodiesterase-4 (PDE4) expression in mouse brain by repeated antidepressant treatment: Comparison with rolipram
2006
2006
Phosphodiesterase-4 influences the PKA phosphorylation status and membrane translocation of G-protein receptor kinase 2 (GRK2) in HEK-293beta2 cells and cardiac myocytes.
Membrane-recruitment of GRK2 (G-protein receptor kinase 2) provides a fundamental step in the desensitization process controlling… 
2005
2005
Retrospective Docking Study of PDE4B Ligands and an Analysis of the Behavior of Selected Scoring Functions
Scoring forms a major obstacle to the success of any docking study. In general, fast scoring functions perform poorly when used… 
2001
2001
Diazepam and rolipram differentially inhibit cyclic AMP-specific phosphodiesterases PDE4A1 and PDE4B3 in the mouse.
2001
2001
Adaptation of cAMP signaling system in SH-SY5Y neuroblastoma cells following expression of a constitutively active stimulatory G protein α, Q227L Gsα
Heterotrimeric GTP-binding proteins (G protein) are known to participate in the transduction of signals from ligand activated… 
2000
2000
Noradrenergic lesions differentially alter the expression of two subtypes of low Km cAMP-sensitive phosphodiesterase type 4 (PDE4A and PDE4B) in rat brain
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