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PD 136450

Known as: PD-136450, PD136450 
National Institutes of Health

Related topics

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2 relations

Broader (2)

IndolesPhenethylamines

Papers overview

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2003
2003
PD-136,450: A CCK2 (gastrin) receptor antagonist with antisecretory, anxiolytic and antiulcer activity
This study investigated the effects of PD-136,450 (PD), a highly selective ligand for the CCK2 receptor, on gastric acid and… 
1999
1999
Pharmacological analysis of CCK2 receptor antagonists using isolated rat stomach ECL cells
Gastrin stimulates rat stomach ECL cells to secrete histamine and pacreastatin, a chromogranin A (CGA)‐derived peptide. The… 
Review
1995
Review
1995
[Gastrin/CCK-B receptor antagonists for a novel antiulcer agent].
Gastrin plays an important role in gastrointestinal functions such as gastric secretion and mucosal growth. The hypergastrinemia… 
1994
1994
A new CCK-B/gastrin receptor antagonist acts as an agonist on the rat pancreas
SummaryThe new CCK-B/gastrin receptor antagonist PD 136450 is of potential value in treating neurologic and psychiatric disorders… 
1992
1992
Effect of gastrin receptor antagonists on gastric acid secretion and gastrin and somatostatin release in the rat stomach.
The effects of two recently developed gastrin receptor antagonists, PD 136450 and L-365,260, on pentagastrin-stimulated acid… 
1991
1991
The effect of CCKB/gastrin antagonists on stimulated gastric acid secretion in the anaesthetized rat
1 The urethane‐anaesthetized, vagotomised rat preparation was used to investigate the effects of the histamine H2‐antagonist… 
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