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PCDH10 gene

Known as: PCDH10, OL-PCDH, KIAA1400 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2006-2016
051020062016

Papers overview

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2016
2016
MALAT1 long ncRNA promotes gastric cancer metastasis by suppressing PCDH10
EZH2, the catalytic component of polycomb repressive complex 2 (PRC2), is frequently overexpressed in human cancers and… (More)
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2012
2012
Role of PCDH10 and its hypermethylation in human gastric cancer.
Epigenetic changes of genomic DNA are involved in the development and progression of many cancers. Aberrant methylation of CpG… (More)
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2012
2012
Frequent epigenetic silencing of PCDH10 by methylation in human colorectal cancer
Aberrant DNA methylation is common in cancer cells. Epigenetic alterations resulting in the loss of tumor suppression gene… (More)
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2011
2011
Identification and characterization of human PCDH10 gene promoter.
Recent studies have suggested roles for PCDH10 as a novel tumor suppressor gene. In our previous work, we located the core… (More)
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2011
2011
Promoter methylation-mediated inactivation of PCDH10 in acute lymphoblastic leukemia contributes to chemotherapy resistance.
PCDH10 has been implicated as a tumor suppressor, since epigenetic alterations of this gene have been noted in multiple tumor… (More)
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2011
2011
Epigenetic inactivation of PCDH10 in human prostate cancer cell lines.
PCDH10 (protocadherin-10), a novel tumour suppressor gene, is down-regulated in several human cancers due to hypermethylation of… (More)
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2010
2010
High-resolution melting analysis of PCDH10 methylation levels in gastric, colorectal and pancreatic cancers.
Protocadherins are celladhesion molecules with 6 or 7 cadherin motifs in their extracellular domain and various cyotoplasmic… (More)
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2009
2009
Protocadherin PCDH10, involved in tumor progression, is a frequent and early target of promoter hypermethylation in cervical cancer.
Cervical cancer (CC) is the second most common cancer in women. Currently, no tractable molecular-based therapeutic targets exist… (More)
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Highly Cited
2008
Highly Cited
2008
Identifying autism loci and genes by tracing recent shared ancestry.
To find inherited causes of autism-spectrum disorders, we studied families in which parents share ancestors, enhancing the role… (More)
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Highly Cited
2006
Highly Cited
2006
Functional epigenetics identifies a protocadherin PCDH10 as a candidate tumor suppressor for nasopharyngeal, esophageal and multiple other carcinomas with frequent methylation
Protocadherins constitute the largest subgroup in the cadherin superfamily of cell adhesion molecules. Their major functions are… (More)
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