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PBS-1086

National Institutes of Health

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CyclohexanonesEpoxy Compounds

Papers overview

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2014
2014
Abstract 1836: Erlotinib induces NF-kappa B dependence that promotes EGFR tyrosine kinase inhibitor resistance in lung adenocarcinoma
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA The vast majority of patients with lung adenocarcinomas… 
2013
2013
Abstract 4631: Pharmacologic inhibition of NF-kappaB overcomes de novo resistance to erlotinib in models of EGFR-mutant lung adenocarcinoma.
Treatment of patients with lung cancers that harbor activating mutations in the kinase domain of EGFR (e.g. L858R, in frame… 
2012
2012
Cancer Therapy : Preclinical Dual Inhibition of Canonical and Noncanonical NFk B Pathways Demonstrates Signi fi cant Antitumor Activities in Multiple Myeloma
Purpose: NF-kB transcription factor plays a key role in the pathogenesis of multiple myeloma in the context of the bone marrow… 
2011
2011
Dual Inhibition of Canonical and Non-Canonical NF-KB Pathway Demonstrates Significant Anti-Tumor Activities in Multiple Myeloma (MM)
Abstract 2902 NF-kB plays a crucial role in the pathogenesis of multiple myeloma (MM). In MM cells, NF-kB pathway is… 
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