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PAXgene Blood Tissue System

Known as: PAXgene 
A system of proprietary reagents and supplies utilizing formalin-free solutions for the simultaneous preservation of histomorphology and biomolecules… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2002-2018
05101520022018

Papers overview

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2011
2011
Blood-based gene expression signatures in non-small cell lung cancer.
PURPOSE Blood-based surrogate markers would be attractive biomarkers for early detection, diagnosis, prognosis, and prediction of… (More)
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2011
2011
Histological Assessment of PAXgene Tissue Fixation and Stabilization Reagents
Within SPIDIA, an EC FP7 project aimed to improve pre analytic procedures, the PAXgene Tissue System (PAXgene), was designed to… (More)
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2009
2009
Variability of gene expression profiles in human blood and lymphoblastoid cell lines
Readily accessible samples such as peripheral blood or cell lines are increasingly being used in large cohorts to characterise… (More)
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2007
2007
Isolation of microarray-grade total RNA, microRNA, and DNA from a single PAXgene blood RNA tube.
We have developed a procedure for isolation of microRNA and genomic DNA in addition to total RNA from whole blood stabilized in… (More)
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Highly Cited
2006
Highly Cited
2006
Signatures of differentially regulated interferon gene expression and vasculotrophism in the peripheral blood cells of systemic sclerosis patients.
OBJECTIVE To obtain a global view of the immunological alterations occurring in early systemic sclerosis (SSc) by transcriptional… (More)
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2006
2006
Effects of globin mRNA reduction methods on gene expression profiles from whole blood.
Excessive globin mRNA in whole blood RNA decreases transcript detection sensitivity and increases signal variation on microarrays… (More)
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2005
2005
Failure of the PAXgene Blood RNA System to maintain mRNA stability in whole blood.
In multicentre studies of malignant and inflammatory diseases, whole blood, cell or tissue samples are often collected for… (More)
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2005
2005
Optimization of the PAXgene blood RNA extraction system for gene expression analysis of clinical samples.
One major problem associated with collecting whole blood from patients for use as a source of RNA in gene expression studies is… (More)
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Highly Cited
2004
Highly Cited
2004
Whole blood and leukocyte RNA isolation for gene expression analyses.
The analysis of gene expression data in clinical medicine has been plagued by the lack of a critical evaluation of accepted… (More)
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Highly Cited
2002
Highly Cited
2002
Stabilization of mRNA expression in whole blood samples.
BACKGROUND Accurate quantification of mRNA in whole blood is made difficult by the simultaneous degradation of gene transcripts… (More)
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