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PAXgene Blood Tissue System

Known as: PAXgene 
A system of proprietary reagents and supplies utilizing formalin-free solutions for the simultaneous preservation of histomorphology and biomolecules… Expand
National Institutes of Health

Papers overview

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2011
2011
Histological Assessment of PAXgene Tissue Fixation and Stabilization Reagents
Within SPIDIA, an EC FP7 project aimed to improve pre analytic procedures, the PAXgene Tissue System (PAXgene), was designed to… Expand
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2010
2010
Proteomic analysis of PAXgene-fixed tissues.
Formalin fixation and paraffin embedding is the standard technique for preserving biological material for both storage and… Expand
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2010
2010
All Our Babies Cohort Study: recruitment of a cohort to predict women at risk of preterm birth through the examination of gene expression profiles and the environment
BackgroundPreterm birth is the leading cause of perinatal morbidity and mortality. Risk factors for preterm birth include a… Expand
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Highly Cited
2008
Highly Cited
2008
Differential gene expression profiles are dependent upon method of peripheral blood collection and RNA isolation
BackgroundRNA isolation and purification steps greatly influence the results of gene expression profiling. There are two… Expand
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Highly Cited
2006
Highly Cited
2006
Effects of globin mRNA reduction methods on gene expression profiles from whole blood.
Excessive globin mRNA in whole blood RNA decreases transcript detection sensitivity and increases signal variation on microarrays… Expand
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Highly Cited
2005
Highly Cited
2005
Optimization of the PAXgene blood RNA extraction system for gene expression analysis of clinical samples.
One major problem associated with collecting whole blood from patients for use as a source of RNA in gene expression studies is… Expand
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2005
2005
Failure of the PAXgene™ Blood RNA System to maintain mRNA stability in whole blood
Abstract In multicentre studies of malignant and inflammatory diseases, whole blood, cell or tissue samples are often collected… Expand
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Highly Cited
2004
Highly Cited
2004
Whole blood and leukocyte RNA isolation for gene expression analyses.
The analysis of gene expression data in clinical medicine has been plagued by the lack of a critical evaluation of accepted… Expand
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Highly Cited
2003
Highly Cited
2003
Assessment of two methods for handling blood in collection tubes with RNA stabilizing agent for surveillance of gene expression profiles with high density microarrays.
Genome-wide expression studies of human blood samples in the context of epidemiologic surveillance are confronted by numerous… Expand
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Highly Cited
2002
Highly Cited
2002
Stabilization of mRNA expression in whole blood samples.
BACKGROUND Accurate quantification of mRNA in whole blood is made difficult by the simultaneous degradation of gene transcripts… Expand
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