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PAX7 gene

Known as: Hup1, PAIRED DOMAIN GENE HuP1, paired box 7 
This gene plays a role in the transcriptional regulation of target genes. It is involved in pattern formation during embryogenesis.
National Institutes of Health

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Related topics

5 relations
Biologic DevelopmentHomo sapiensPAX7 protein, humanTranscriptional Regulation
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Papers overview

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Highly Cited
2014
Highly Cited
2014
PAX7 expression defines germline stem cells in the adult testis.
Spermatogenesis is a complex, multistep process that maintains male fertility and is sustained by rare germline stem cells… Expand
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Highly Cited
2013
Highly Cited
2013
Pax7 is critical for the normal function of satellite cells in adult skeletal muscle
Significance Skeletal muscle exhibits a remarkable ability to regenerate, a process that has been demonstrated to be dependent on… Expand
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Highly Cited
2012
Highly Cited
2012
Transcriptional dominance of Pax7 in adult myogenesis is due to high-affinity recognition of homeodomain motifs.
Pax3 and Pax7 regulate stem cell function in skeletal myogenesis. However, molecular insight into their distinct roles has… Expand
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Highly Cited
2010
Highly Cited
2010
miR-206 and -486 Induce Myoblast Differentiation by Downregulating Pax7 † † Supplemental material for this article may be found at http://dx.doi.org/10.1128/MCB.01009-10.
ABSTRACT The Pax7 transcription factor is required for muscle satellite cell biogenesis and specification of the myogenic… Expand
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Highly Cited
2009
Highly Cited
2009
Id3 is a direct transcriptional target of Pax7 in quiescent satellite cells.
Pax7 is a key regulator of skeletal muscle stem cells and is required along with Pax3 to generate skeletal muscle precursors. We… Expand
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Highly Cited
2004
Highly Cited
2004
Divergent functions of murine Pax3 and Pax7 in limb muscle development.
Pax genes encode evolutionarily conserved transcription factors that play critical roles in development. Pax3 and Pax7 constitute… Expand
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Highly Cited
2003
Highly Cited
2003
PAX7 expression in embryonal rhabdomyosarcoma suggests an origin in muscle satellite cells
Rhabdomyosarcoma (RMS) is a common paediatric soft tissue sarcoma that resembles developing foetal skeletal muscle. Tumours of… Expand
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Highly Cited
1999
Highly Cited
1999
PAX3 and PAX7 exhibit conserved cis-acting transcription repression domains and utilize a common gain of function mechanism in alveolar rhabdomyosarcoma
The t(2;13) and t(1;13) translocations of alveolar rhabdomyosarcoma (ARMS) result in chimeric PAX3-FKHR or PAX7-FKHR… Expand
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Highly Cited
1999
Highly Cited
1999
Predominant expression of alternative PAX3 and PAX7 forms in myogenic and neural tumor cell lines.
PAX3 and PAX7 are closely related paired box family members expressed during early neural and myogenic development. Assay of PAX3… Expand
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Review
1998
Review
1998
The role of Pax3 and Pax7 in development and cancer.
  • A. Mansouri
  • Critical reviews in oncogenesis
  • 1998
    • Corpus ID: 46672066
Pax genes consist of a family of transcription factors that are essentially required for the genesis of a variety of tissues and… Expand
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