PAX7 gene

Known as: Hup1, PAIRED DOMAIN GENE HuP1, paired box 7 
This gene plays a role in the transcriptional regulation of target genes. It is involved in pattern formation during embryogenesis.
National Institutes of Health

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Biologic DevelopmentHomo sapiensPAX7 protein, humanTranscriptional Regulation
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Papers overview

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2014
2014
PAX7 expression defines germline stem cells in the adult testis.
Spermatogenesis is a complex, multistep process that maintains male fertility and is sustained by rare germline stem cells… (More)
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Highly Cited
2013
Highly Cited
2013
Pax7 is critical for the normal function of satellite cells in adult skeletal muscle.
Extensive analyses of mice carrying null mutations in paired box 7 (Pax7) have confirmed the progressive loss of the satellite… (More)
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2012
2012
Transcriptional dominance of Pax7 in adult myogenesis is due to high-affinity recognition of homeodomain motifs.
Pax3 and Pax7 regulate stem cell function in skeletal myogenesis. However, molecular insight into their distinct roles has… (More)
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Highly Cited
2011
Highly Cited
2011
miR-206 and -486 induce myoblast differentiation by downregulating Pax7.
The Pax7 transcription factor is required for muscle satellite cell biogenesis and specification of the myogenic precursor… (More)
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2009
2009
Id3 is a direct transcriptional target of Pax7 in quiescent satellite cells.
Pax7 is a key regulator of skeletal muscle stem cells and is required along with Pax3 to generate skeletal muscle precursors. We… (More)
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2008
2008
Genome-wide discovery of Pax7 target genes during development.
Pax7 plays critical roles in development of brain, spinal cord, neural crest, and skeletal muscle. As a sequence-specific DNA… (More)
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Highly Cited
2004
Highly Cited
2004
Divergent functions of murine Pax3 and Pax7 in limb muscle development.
Pax genes encode evolutionarily conserved transcription factors that play critical roles in development. Pax3 and Pax7 constitute… (More)
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2003
2003
PAX7 expression in embryonal rhabdomyosarcoma suggests an origin in muscle satellite cells
Rhabdomyosarcoma (RMS) is a common paediatric soft tissue sarcoma that resembles developing foetal skeletal muscle. Tumours of… (More)
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1998
1998
Correlation between tectum formation and expression of two PAX family genes, PAX7 and PAX6, in avian brains.
Heterotopic transplantation of brain vesicles between chick and quail were performed, and the correlation between tectum… (More)
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Review
1998
Review
1998
The role of Pax3 and Pax7 in development and cancer.
Pax genes consist of a family of transcription factors that are essentially required for the genesis of a variety of tissues and… (More)
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