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PAX3 gene

Known as: paired box 3, Paired Box Gene 3 (Waardenburg Syndrome 1) Gene, HUP2 
This gene plays a role in the transcriptional activation of target genes. It is involved in melanogenesis, neurogenesis and skeletal muscle… Expand
National Institutes of Health

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Related topics

9 relations
ApoptosisBiologic DevelopmentHomo sapiensOrganogenesis
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PAX3 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2007
Review
2007
The role of Pax genes in the development of tissues and organs: Pax3 and Pax7 regulate muscle progenitor cell functions.
Pax genes play key roles in the formation of tissues and organs during embryogenesis. Pax3 and Pax7 mark myogenic progenitor… Expand
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Highly Cited
2007
Highly Cited
2007
Regulation of Pax3 by Proteasomal Degradation of Monoubiquitinated Protein in Skeletal Muscle Progenitors
Pax3 and Pax7 play distinct but overlapping roles in developmental and postnatal myogenesis. The mechanisms involved in the… Expand
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Highly Cited
2005
Highly Cited
2005
A Pax3/Pax7-dependent population of skeletal muscle progenitor cells
During vertebrate development, successive phases of embryonic and fetal myogenesis lead to the formation and growth of skeletal… Expand
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Highly Cited
2005
Highly Cited
2005
Msx1 and Pax3 cooperate to mediate FGF8 and WNT signals during Xenopus neural crest induction.
FGF, WNT, and BMP signaling promote neural crest formation at the neural plate boundary in vertebrate embryos. To understand how… Expand
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Highly Cited
2005
Highly Cited
2005
Neural crest determination by co-activation of Pax3 and Zic1 genes in Xenopus ectoderm
A number of regulatory genes have been implicated in neural crest development. However, the molecular mechanism of how neural… Expand
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Highly Cited
2004
Highly Cited
2004
Divergent functions of murine Pax3 and Pax7 in limb muscle development.
Pax genes encode evolutionarily conserved transcription factors that play critical roles in development. Pax3 and Pax7 constitute… Expand
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Highly Cited
2000
Highly Cited
2000
Interaction among SOX10, PAX3 and MITF, three genes altered in Waardenburg syndrome.
Waardenburg syndrome (WS) is an autosomal dominant disorder with an incidence of 1 in 40 000 that manifests with sensorineural… Expand
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Highly Cited
2000
Highly Cited
2000
Transcription factor hierarchy in Waardenburg syndrome: regulation of MITF expression by SOX10 and PAX3
Abstract. Waardenburg syndrome (WS) is associated with neural crest-derived melanocyte deficiency caused by mutations in either… Expand
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Highly Cited
1996
Highly Cited
1996
Pax3 modulates expression of the c-Met receptor during limb muscle development.
Pax3 is a transcription factor whose expression has been used as a marker of myogenic precursor cells arising in the lateral… Expand
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Highly Cited
1993
Highly Cited
1993
Fusion of PAX3 to a member of the forkhead family of transcription factors in human alveolar rhabdomyosarcoma.
Alveolar rhabdomyosarcoma, a malignant tumor of skeletal muscle, is characterized by a chromosomal translocation, t(2;13)(q35;q14… Expand
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