PAX3 gene

Known as: paired box 3, Paired Box Gene 3 (Waardenburg Syndrome 1) Gene, HUP2 
This gene plays a role in the transcriptional activation of target genes. It is involved in melanogenesis, neurogenesis and skeletal muscle… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2018
0102019922018

Papers overview

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2008
2008
The Pax3/7 gene family has a fundamental and conserved role during neural crest formation. In people, PAX3 mutation causes… (More)
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2001
2001
Deregulated expression of the transcription factor PAX3 was observed previously in several tumors like rhabdomyosarcoma and Ewing… (More)
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Highly Cited
2000
Highly Cited
2000
Waardenburg syndrome (WS) is an autosomal dominant disorder with an incidence of 1 in 40 000 that manifests with sensorineural… (More)
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Highly Cited
2000
Highly Cited
2000
Waardenburg syndrome (WS) is associated with neural crest-derived melanocyte deficiency caused by mutations in either one of… (More)
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2000
2000
The aberrant expression of the transcription factors PAX3 and PAX3/FKHR associated with rhabdomyosarcoma (RMS), solid tumors… (More)
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Highly Cited
1999
Highly Cited
1999
Alveolar rhabdomyosarcoma is an aggressive pediatric cancer of striated muscle characterized in 60% of cases by a t(2;13)(q35;q14… (More)
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1999
1999
PAX3 is a member of the paired box family of transcription factors that function during embryogenesis and cancer epigenesis… (More)
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Highly Cited
1998
Highly Cited
1998
Waardenburg syndrome (WS) is a hereditary disorder that causes hypopigmentation and hearing impairment. Depending on additional… (More)
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Highly Cited
1995
Highly Cited
1995
Alveolar rhabdomyosarcomas are pediatric solid tumors with a hallmark cytogenetic abnormality: translocation of chromosomes 2 and… (More)
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Highly Cited
1993
Highly Cited
1993
We have determined that PAX3 (found previously to be mutated in Waardenburg syndrome) is the chromosome 2 locus rearranged by the… (More)
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