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PAX2 wt Allele

Known as: PAX2, Paired Box 2 wt Allele 
Human PAX2 wt allele is located in the vicinity of 10q24.31 and is approximately 84 kb in length. This allele, which encodes paired box protein Pax-2… 
National Institutes of Health

Related topics

Related topics

8 relations
Homo sapiensNeurogenesisPAX2 Transcription FactorPAX6 wt Allele

Broader (1)

PAX2 gene

Papers overview

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2011
2011
Vesicoureteral Reflux and Other Urinary Tract Malformations in Mice Compound Heterozygous for Pax2 and Emx2
Congenital anomalies of the kidney and urinary tract (CAKUT) are the most common cause of chronic kidney disease in children… 
2011
2011
PAX2 Expression in Wilms Tumors and Other Childhood Neoplasms
PAX2 plays an important role in kidney development; although small studies have demonstrated PAX2 expression in Wilms tumors (WT… 
Review
2004
Review
2004
Genetic determination of nephrogenesis: the Pax/Eya/Six gene network
Development of the kidney serves as a paradigm to understand the mechanisms underlying the formation of an organ. The first sign… 
2004
2004
Rescue of defective branching nephrogenesis in renal-coloboma syndrome by the caspase inhibitor, Z-VAD-fmk.
In renal-coloboma syndrome (RCS), null mutations of the PAX2 gene cause renal hypoplasia due to a congenital deficit of nephrons… 
Highly Cited
2000
Highly Cited
2000
Functional equivalence of the transcription factors Pax2 and Pax5 in mouse development.
Pax2 and Pax5 arose by gene duplication at the onset of vertebrate evolution and have since diverged in their developmental… 
Review
1998
Review
1998
The role of PAX2 in normal and abnormal development of the urinary tract
Abstract. The molecular etiology of many urinary tract abnormalities in children remains unknown, but a number of genes with a… 
Review
1998
Review
1998
What PAX Genes Do in the Kidney
Of the nine known PAX genes, only two (PAX2 and PAX8) are expressed in the developing kidney. Genetic evidence in mice and humans… 
Highly Cited
1997
Highly Cited
1997
Cooperation of Pax2 and Pax5 in midbrain and cerebellum development.
Midbrain and cerebellum development depends on an organizing center that is located at the midbrain-hindbrain junction of the… 
Review
1997
Review
1997
Cooperation of Pax2 and Pax5 in midbrain and cerebellum development
Midbrain and cerebellum development de- pendsonanorganizingcenterthatislocatedatthemidbrain… 
Highly Cited
1995
Highly Cited
1995
Involvement of wnt1 and pax2 in the formation of the midbrain-hindbrain boundary in the zebrafish gastrula.
The secreted signalling molecule encoded by the wnt1 gene and the paired box-containing pax2 gene are thought to play an integral… 
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