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PAX2 Transcription Factor

Known as: Paired Box Protein Pax 2, Factor PAX2, Transcription, Paired Box Gene 2 Protein 
Paired box protein PAX-2 (416aa, ~45 kD) is encoded by the human PAX2 gene. This soluble, nuclear protein plays a role in transcription by RNA… 
National Institutes of Health

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Related topics

20 relations
DNA-Binding ProteinsGenes, RegulatorHomo sapiensIn Blood

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Pax2 protein, mousepax2a protein, zebrafish

Papers overview

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Highly Cited
2009
Highly Cited
2009
The murine Fgfrl1 receptor is essential for the development of the metanephric kidney.
2009
2009
Precursors with Glial Fibrillary Acidic Protein Promoter Activity Transiently Generate GABA Interneurons in the Postnatal Cerebellum
Neural stem or progenitor cells (NSC/NPCs) able to generate the different neuron and glial cell types of the cerebellum have been… 
2005
2005
Isolation and characterization of murine retinal astrocytes.
PURPOSE To isolate and characterize primary retinal astrocytes in culture (RAC) from wild-type and transgenic mice to aid the… 
Highly Cited
2003
Highly Cited
2003
Ureteric bud apoptosis and renal hypoplasia in transgenic PAX2-Bax fetal mice mimics the renal-coloboma syndrome.
In humans, PAX2 haploinsufficiency causes renal-coloboma syndrome (RCS) involving eye abnormalities, renal hypoplasia, and renal… 
Review
2002
Review
2002
PAX genes in development and disease: the role of PAX2 in urogenital tract development.
PAX genes play an important role in fetal development. Moreover, heterozygous mutations in several PAX genes cause human disease… 
1998
1998
Aphakia (ak), a mouse mutation affecting early eye development: fine mapping, consideration of candidate genes and altered Pax6 and Six3 gene expression pattern.
The homozygous mouse mutant aphakia (ak) has been characterized by bilaterally aphakic eyes without a pupil [Varnum DS, Stevens… 
Highly Cited
1997
Highly Cited
1997
Toward cloning of a novel ataxia gene: refined assignment and physical map of the IOSCA locus (SCA8) on 10q24.
Infantile onset spinocerebellar ataxia (IOSCA) is a progressive neurological disorder of unknown etiology. It is inherited as an… 
Highly Cited
1996
Highly Cited
1996
The paired-box transcription factor, PAX2, positively modulates expression of the Wilms' tumor suppressor gene (WT1).
The Wilms' tumor suppressor gene, wt1, encodes a zinc finger protein which functions as a transcriptional regulator. Expression… 
Highly Cited
1996
Highly Cited
1996
Regionalized expression of Nkx5-1, Nkx5-2, Pax2 and sek genes during mouse inner ear development
Highly Cited
1994
Highly Cited
1994
A gene for Crouzon craniofacial dysostosis maps to the long arm of chromosome 10
Crouzon craniofacial dysostosis (CFD) is an autosomal dominant craniofacial disorder characterized by premature craniosynostosis… 
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