PARL gene

Known as: PSARL1, PRO2207, PARL 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1986-2018
02419862018

Papers overview

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2017
2017
Mitochondria drive apoptosis by releasing pro-apoptotic proteins that promote caspase activation in the cytosol. The rhomboid… (More)
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2015
2015
Mutations in PINK1 and PARK2/Parkin are a main risk factor for familial Parkinson disease. While the physiological mechanism of… (More)
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Highly Cited
2013
Highly Cited
2013
PINK1, a mitochondrial serine/threonine kinase, is the product of a gene mutated in an autosomal recessive form of Parkinson… (More)
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2012
2012
The mitochondria-shaping protein optic atrophy 1 (OPA1) has genetically distinguishable roles in mitochondrial morphology and… (More)
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Highly Cited
2011
Highly Cited
2011
Intramembrane proteolysis is a conserved mechanism that regulates a variety of cellular processes ranging from transcription… (More)
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2011
2011
The mitochondrial rhomboid protease Parl governs apoptosis, morphology, metabolism and might be implicated in Parkinson's disease… (More)
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Highly Cited
2010
Highly Cited
2010
PINK1 is a mitochondrial kinase mutated in some familial cases of Parkinson's disease. It has been found to work in the same… (More)
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2010
2010
Type 2 diabetes mellitus (T2DM) and aging are characterized by insulin resistance and impaired mitochondrial energetics. In lower… (More)
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2009
2009
Normal tension glaucoma is a major subtype of glaucoma, associated with intraocular pressures that are within the statistically… (More)
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2004
2004
Regulated intramembrane proteolysis (RIP) is an emerging paradigm in signal transduction. RIP is mediated by intramembrane… (More)
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