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P-glycoprotein Inhibitor

Known as: P-gp inhibitor 
Any compound or agent that acts to prevent the activity of P-glycoprotein.
National Institutes of Health

Papers overview

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2020
2020
Synthesis, biological evaluation and preclinical study of a novel 99mTc-peptide: A targeting probe of amyloid-β plaques as a possible diagnostic agent for Alzheimer's disease.
Highly Cited
2019
Highly Cited
2019
Human iPSC-derived blood-brain barrier microvessels: validation of barrier function and endothelial cell behavior.
Highly Cited
2017
Highly Cited
2017
Co-delivery of docetaxel and verapamil by reduction-sensitive PEG-PLGA-SS-DTX conjugate micelles to reverse the multi-drug resistance of breast cancer.
2015
2015
Novel dietary lipid-based self-nanoemulsifying drug delivery systems of paclitaxel with p-gp inhibitor: implications on cytotoxicity and biopharmaceutical performance
Objectives: This work describes the development and characterization of novel self-nanoemulsifying drug delivery systems (SNEDDS… 
Highly Cited
2008
Highly Cited
2008
Intestinal Absorption Mechanisms of Prenylated Flavonoids Present in the Heat-Processed Epimedium koreanum Nakai (Yin Yanghuo)
PurposeThe purpose is to determine absorption mechanism of five bioactive prenylated flavonoids (baohuoside I, icariin, epimedine… 
Highly Cited
2007
Highly Cited
2007
Minocycline and riluzole brain disposition: interactions with p‐glycoprotein at the blood–brain barrier
Amyotrophic lateral sclerosis is a neurodegenerative fatal disease. The only drug recognized to increase the survival time is… 
Highly Cited
2007
Highly Cited
2007
Oral administration of a potent and selective non-peptidic BACE-1 inhibitor decreases beta-cleavage of amyloid precursor protein and amyloid-beta production in vivo.
Generation and deposition of the amyloid beta (Abeta) peptide following proteolytic processing of the amyloid precursor protein… 
2006
2006
Role of P-glycoprotein in tissue uptake of indinavir in rat.
  • M. Hamidi
  • Life sciences
  • 2006
  • Corpus ID: 30127154
2004
2004
Toxicity of Quinacrine Can Be Reduced By Co-Administration of P-Glycoprotein Inhibitor in Sporadic Creutzfeldt-Jakob Disease
Abstract1. Recent publication has suggested that quinacrine may be a candidate for treatment of Creutzfeldt-Jakob disease (CJD… 
Highly Cited
1995
Highly Cited
1995
Effect of the p-glycoprotein inhibitor, cyclosporin A, on the distribution of rhodamine-123 to the brain: an in vivo microdialysis study in freely moving rats.
The p-glycoprotein is a transmembrane efflux transporter found on the luminal side of the capillary endothelial cells that… 
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