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P-glycoprotein Inhibitor

Known as: P-gp inhibitor 
Any compound or agent that acts to prevent the activity of P-glycoprotein.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Synthesis, biological evaluation and preclinical study of a novel 99mTc-peptide: A targeting probe of amyloid-β plaques as a possible diagnostic agent for Alzheimer's disease.
2019
2019
Spontaneous hemopericardium and cardiac tamponade induced by dabigatran in combination with p-glycoprotein inhibitor
ABSTRACT Direct oral anticoagulants have been presented as a novel option for prevention and treatment of nonvalvular atrial… 
2019
2019
Characterization of Major and Clinically Relevant Non-Major Bleeds in the APEX Trial
Abstract Background Among medically ill patients treated with thromboprophylaxis, betrixaban was not associated with an increase… 
2015
2015
Inhibition of multidrug transporter in tumor endothelial cells enhances antiangiogenic effects of low-dose metronomic paclitaxel.
2013
2013
Development of a combinational drug-loaded nanoparticle for improving paclitaxel uptake into multidrug resistant breast cancer cells
SUMMARY Paclitaxel have been used in the treatment of wide range of cancers, but its entry into cancer cell is restricted by p… 
2011
2011
Combination of Curcumin and Paclitaxel-loaded Solid Lipid Nanoparticles to Overcome Multidrug Resistance
Multi-drug resistance (MDR) has been known as a major hurdle in cancer chemotherapy. One of the most clinically significant… 
2006
2006
Tetraethylammonium and nicotine transport by the Malpighian tubules of insects.
2004
2004
Toxicity of Quinacrine Can Be Reduced By Co-Administration of P-Glycoprotein Inhibitor in Sporadic Creutzfeldt-Jakob Disease
Abstract1. Recent publication has suggested that quinacrine may be a candidate for treatment of Creutzfeldt-Jakob disease (CJD… 
Highly Cited
2002
Highly Cited
2002
Pharmacokinetic role of P-glycoprotein in oral bioavailability and intestinal secretion of grepafloxacin in vivo.
The purpose of this study was to clarify the contribution of P-glycoprotein to the bioavailability and intestinal secretion of… 
2000
2000
Contrasting effects of aspirin on prostate cancer cells: Suppression of proliferation and induction of drug resistance
Aspirin is widely used as a preventive measure against occlusive vascular diseases. Since the age group in which aspirin use has… 
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