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P-glycoprotein Inhibitor
Known as:
P-gp inhibitor
Any compound or agent that acts to prevent the activity of P-glycoprotein.
National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Synthesis, biological evaluation and preclinical study of a novel 99mTc-peptide: A targeting probe of amyloid-β plaques as a possible diagnostic agent for Alzheimer's disease.
Safura Jokar
,
Hossein Behnammanesh
,
+7 authors
D. Beiki
Bioorganic chemistry
2020
Corpus ID: 216130192
Highly Cited
2019
Highly Cited
2019
Human iPSC-derived blood-brain barrier microvessels: validation of barrier function and endothelial cell behavior.
Raleigh M. Linville
,
Jackson G. DeStefano
,
+10 authors
P. Searson
Biomaterials
2019
Corpus ID: 53215451
Highly Cited
2017
Highly Cited
2017
Co-delivery of docetaxel and verapamil by reduction-sensitive PEG-PLGA-SS-DTX conjugate micelles to reverse the multi-drug resistance of breast cancer.
Yuanyuan Guo
,
Wenxiu He
,
Shengfeng Yang
,
D. Zhao
,
Zhonghao Li
,
Y. Luan
Colloids and surfaces. B, Biointerfaces
2017
Corpus ID: 6858742
2015
2015
Novel dietary lipid-based self-nanoemulsifying drug delivery systems of paclitaxel with p-gp inhibitor: implications on cytotoxicity and biopharmaceutical performance
Premjeet Singh Sandhu
,
S. Beg
,
F. Mehta
,
Bhupinder Singh
,
P. Trivedi
Expert opinion on drug delivery
2015
Corpus ID: 31231587
Objectives: This work describes the development and characterization of novel self-nanoemulsifying drug delivery systems (SNEDDS…
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Highly Cited
2008
Highly Cited
2008
Intestinal Absorption Mechanisms of Prenylated Flavonoids Present in the Heat-Processed Epimedium koreanum Nakai (Yin Yanghuo)
Yan Chen
,
Y. Zhao
,
X. Jia
,
M. Hu
Pharmaceutical Research
2008
Corpus ID: 7077089
PurposeThe purpose is to determine absorption mechanism of five bioactive prenylated flavonoids (baohuoside I, icariin, epimedine…
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Highly Cited
2007
Highly Cited
2007
Minocycline and riluzole brain disposition: interactions with p‐glycoprotein at the blood–brain barrier
A. Milane
,
C. Fernandez
,
Sarah Vautier
,
G. Bensimon
,
V. Meininger
,
R. Farinotti
Journal of neurochemistry
2007
Corpus ID: 45315168
Amyotrophic lateral sclerosis is a neurodegenerative fatal disease. The only drug recognized to increase the survival time is…
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Highly Cited
2007
Highly Cited
2007
Oral administration of a potent and selective non-peptidic BACE-1 inhibitor decreases beta-cleavage of amyloid precursor protein and amyloid-beta production in vivo.
I. Hussain
,
J. Hawkins
,
+14 authors
John B Davis
Journal of neurochemistry
2007
Corpus ID: 40054294
Generation and deposition of the amyloid beta (Abeta) peptide following proteolytic processing of the amyloid precursor protein…
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2006
2006
Role of P-glycoprotein in tissue uptake of indinavir in rat.
M. Hamidi
Life sciences
2006
Corpus ID: 30127154
2004
2004
Toxicity of Quinacrine Can Be Reduced By Co-Administration of P-Glycoprotein Inhibitor in Sporadic Creutzfeldt-Jakob Disease
K. Satoh
,
S. Shirabe
,
+5 authors
S. Katamine
Cellular and Molecular Neurobiology
2004
Corpus ID: 12612884
Abstract1. Recent publication has suggested that quinacrine may be a candidate for treatment of Creutzfeldt-Jakob disease (CJD…
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Highly Cited
1995
Highly Cited
1995
Effect of the p-glycoprotein inhibitor, cyclosporin A, on the distribution of rhodamine-123 to the brain: an in vivo microdialysis study in freely moving rats.
Q. Wang
,
H. Yang
,
D. Miller
,
W. Elmquist
Biochemical and biophysical research…
1995
Corpus ID: 22510977
The p-glycoprotein is a transmembrane efflux transporter found on the luminal side of the capillary endothelial cells that…
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