Skip to search formSkip to main contentSkip to account menu

Otenabant

Known as: 1-(8-(2-Chlorophenyl)-9-(4-Chlorophenyl)-9H-Purin-6-yl)-4-(Ethylamino)Piperidine-4-Carboxamide, 4-Piperidinecarboxamide, 1-(8-(2-Chlorophenyl)-9-(4-Chlorophenyl)-9H-Purin-6-yl)-4- (Ethylamino)- 
National Institutes of Health

Related topics

Related topics

1 relation

Narrower (1)

CP-945,598

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Advances in the Understanding of the Cannabinoid Receptor 1 - Focusing on the Inverse Agonists Interactions
BACKGROUND Cannabinoid Receptor 1 (CB1) is a membrane protein prevalent in the central nervous system, whose crystallographic… 
2019
2019
Functionalized 6-(piperidin-1-yl)-8,9-diphenyl purines as inverse agonists of the CB1 receptor - SAR efforts towards selectivity and peripheralization.
2019
2019
Functionalized 6-(Piperidin-1-yl)-8,9-Diphenyl Purines as Peripherally Restricted Inverse Agonists of the CB1 Receptor.
Antagonists of peripheral type 1 cannabinoid receptors (CB1) have potential utility in the treatment of various diseases… 
2017
2017
Pharmacological comparison of traditional and non-traditional cannabinoid receptor 1 blockers in rodent models in vivo
2015
2015
(4-(Bis(4-Fluorophenyl)Methyl)Piperazin-1-yl)(Cyclohexyl)Methanone Hydrochloride (LDK1229): A New Cannabinoid CB1 Receptor Inverse Agonist from the Class of Benzhydryl Piperazine Analogs
Some inverse agonists of cannabinoid receptor type 1 (CB1) have been demonstrated to be anorectic antiobesity drug candidates… 
2014
2014
Relative Contributions of Cytochrome CYP 3 A 4 Versus CYP 3 A 5 for CYP 3 A-Cleared Drugs Assessed In Vitro Using a CYP 3 A 4-Selective Inactivator ( CYP 3 cide ) s
Metabolism by cytochrome P4503A (CYP3A) is the most prevalent clearance pathway for drugs. Designation of metabolism by CYP3A… 
2013
2013
Peripherally selective diphenyl purine antagonist of the CB1 receptor.
Antagonists of the CB1 receptor can be useful in the treatment of several important disorders. However, to date, the only… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)