Osteosarcoma

Known as: osteochondrosarcoma, Tumors, Osteosarcoma, BONE CANCER, OSTEOGENIC SARCOMA 
A usually aggressive malignant bone-forming mesenchymal neoplasm, predominantly affecting adolescents and young adults. It usually involves bones and… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Emerging evidence indicates the presence of tumor-initiating cells (TIC) or cancer stem cells in osteosarcoma. However, no study… (More)
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Highly Cited
2009
Highly Cited
2009
In this study, high-throughput microRNA (miRNA) expression analysis revealed that the expression of miR-140 was associated with… (More)
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Highly Cited
2009
Highly Cited
2009
Wnt signaling increases bone mass by stimulating osteoblast lineage commitment and expansion and forms the basis for novel… (More)
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Highly Cited
2008
Highly Cited
2008
Mutation of the RB-1 and p53 tumor suppressors is associated with the development of human osteosarcoma. With the goal of… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND The evaluation variables influencing systemic and local recurrence and final outcome are extremely important in… (More)
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Review
2004
Review
2004
Bone morphogenetic proteins (BMPs) are multi-functional growth factors that belong to the transforming growth factor beta… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Rothmund-Thomson syndrome (RTS) is an autosomal recessive disorder associated with an increased predisposition to… (More)
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Highly Cited
2002
Highly Cited
2002
Neoplasms have a striking tendency to metastasize or "home" to bone. Hematopoietic cells also home to bone during embryonic… (More)
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Highly Cited
1990
Highly Cited
1990
Mutations in the p53 gene have been associated with a wide range of human tumors, including osteosarcomas. Although it has been… (More)
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Highly Cited
1986
Highly Cited
1986
The genomes of various tumour cells contain mutant oncogenes that act dominantly, in that their effects can be observed when they… (More)
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