Osteopetrosis

Known as: Disease, Albers-Schonberg, Osteosclerosis Fragilis, Marble bone disease 
A rare genetic disorder inherited in an autosomal dominant, autosomal recessive, or X-linked recessive pattern. In the majority of cases it is caused… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Bisphosphonates potently inhibit the recruitment, activity, and lifespan of osteoclasts and, in so doing, increase bone mineral… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
The effects of colony-stimulating factor 1 (CSF-1), the primary regulator of mononuclear phagocyte production, are thought to be… (More)
  • figure 1
  • table 1
  • figure 2
  • table 2
  • figure 3
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Chloride channels play important roles in the plasma membrane and in intracellular organelles. Mice deficient for the… (More)
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Osteopetrosis includes a group of inherited diseases in which inadequate bone resorption is caused by osteoclast dysfunction… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Bone resorption and remodeling is an intricately controlled, physiological process that requires the function of osteoclasts. The… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Solubilization of bone mineral by osteoclasts depends on the formation of an acidic extracellular compartment through the action… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • table 1
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Cathepsin K is a recently identified lysosomal cysteine proteinase. It is abundant in osteoclasts, where it is believed to play a… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 3
  • table 1
Is this relevant?
Highly Cited
1997
Highly Cited
1997
A novel secreted glycoprotein that regulates bone resorption has been identified. The protein, termed Osteoprotegerin (OPG), is a… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1997
Highly Cited
1997
The nfkb1 and nfkb2 genes encode closely related products regulating immune and inflammatory responses. Their role during… (More)
Is this relevant?
Highly Cited
1990
Highly Cited
1990
MICE homozygous for the recessive mutation osteopetrosis (op) on chromosome 3 have a restricted capacity for bone remodelling… (More)
Is this relevant?