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Osteocalcin

Known as: Bone Gla Protein, Gamma-Carboxyglutamic Acid-Containing Protein, Osteocalcin (human reduced), 3-de-L-tyrosine-4-de-L-glutamine-5-de-L-tryptophan-6-de-L-leucine-9-L-serine-12-L-serine-19-L-threonine-22-L-glutamine-28-L-alanine-33-L-serine-35-L-glutamine-36-L-tyrosine-38-L-leucine-39-L-lysine-40-L-threonine-43-L-lysine-4 
Vitamin K-dependent calcium-binding protein synthesized by OSTEOBLASTS and found primarily in BONES. Serum osteocalcin measurements provide a… Expand
National Institutes of Health

Related topics

Related topics

26 relations
BGLAP geneCell AdhesionCell MovementExtracellular Matrix
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Broader (2)

Calcium-Binding ProteinsExtracellular Matrix Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Expression of Odontogenic and Osteogenic Markers in DPSCs and SHED: A Review.
The odontogenic and osteogenic potential of dental pulp stem cells (DPSCs) and stem cells from human exfoliated deciduous tooth… Expand
Highly Cited
2009
Highly Cited
2009
Association between serum osteocalcin and markers of metabolic phenotype.
CONTEXT Osteocalcin has been reported to contribute to the regulation of glucose tolerance and insulin secretion and sensitivity… Expand
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Highly Cited
2009
Highly Cited
2009
Plasma Osteocalcin Is Inversely Related to Fat Mass and Plasma Glucose in Elderly Swedish Men
The osteoblast‐derived protein osteocalcin has recently been shown to affect adiposity and glucose homeostasis in mice… Expand
Highly Cited
2003
Highly Cited
2003
Bone recognition mechanism of porcine osteocalcin from crystal structure
Osteocalcin is the most abundant noncollagenous protein in bone, and its concentration in serum is closely linked to bone… Expand
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Highly Cited
1998
Highly Cited
1998
Fourier transform infrared microspectroscopic analysis of bones of osteocalcin-deficient mice provides insight into the function of osteocalcin.
Osteocalcin, the gamma-carboxyglutamic acid-containing protein, which in most species is the predominant noncollagenous protein… Expand
Highly Cited
1997
Highly Cited
1997
Targeted Disruption of Cbfa1Results in a Complete Lack of Bone Formation owing to Maturational Arrest of Osteoblasts
A transcription factor, Cbfa1, which belongs to the runt-domain gene family, is expressed restrictively in fetal development. To… Expand
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Highly Cited
1997
Highly Cited
1997
Undercarboxylated osteocalcin measured with a specific immunoassay predicts hip fracture in elderly women: the EPIDOS Study.
Increased levels of circulating undercarboxylated osteocalcin (ucOC), measured indirectly with the hydroxyapatite (HAP) binding… Expand
Highly Cited
1992
Highly Cited
1992
Contribution of trans-acting factor alleles to normal physiological variability: vitamin D receptor gene polymorphism and circulating osteocalcin.
Osteocalcin, the most abundant noncollagenous protein in bone, is a marker of bone turnover in normal and disease states. Its… Expand
Highly Cited
1989
Highly Cited
1989
Structure of the rat osteocalcin gene and regulation of vitamin D-dependent expression.
The osteocalcin gene encodes a 6-kDa polypeptide, which represents one of the most abundant noncollagenous bone proteins, and the… Expand
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Highly Cited
1982
Highly Cited
1982
Calcium-dependent alpha-helical structure in osteocalcin.
Osteocalcin is an abundant Ca2+-binding protein of bone containing three residues of vitamin K dependent gamma-carboxyglutamic… Expand
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