FAQ

Osteocalcin

Known as: Bone Gla Protein, Gamma-Carboxyglutamic Acid-Containing Protein, Osteocalcin (human reduced), 3-de-L-tyrosine-4-de-L-glutamine-5-de-L-tryptophan-6-de-L-leucine-9-L-serine-12-L-serine-19-L-threonine-22-L-glutamine-28-L-alanine-33-L-serine-35-L-glutamine-36-L-tyrosine-38-L-leucine-39-L-lysine-40-L-threonine-43-L-lysine-4 
Vitamin K-dependent calcium-binding protein synthesized by OSTEOBLASTS and found primarily in BONES. Serum osteocalcin measurements provide a… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1959-2018
010020030019592018

Related topics

Related topics

26 relations
BGLAP geneCell AdhesionCell MovementExtracellular Matrix
(More)

Broader (2)

Calcium-Binding ProteinsExtracellular Matrix Proteins

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Osteocalcin
physiological aspects
Extracellular Matrix
cell growth
Cell Adhesion
Wound Healing

Papers overview

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Highly Cited
2009
Highly Cited
2009
Association between serum osteocalcin and markers of metabolic phenotype.
CONTEXT Osteocalcin has been reported to contribute to the regulation of glucose tolerance and insulin secretion and sensitivity… (More)
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Highly Cited
2009
Highly Cited
2009
Plasma osteocalcin is inversely related to fat mass and plasma glucose in elderly Swedish men.
The osteoblast-derived protein osteocalcin has recently been shown to affect adiposity and glucose homeostasis in mice… (More)
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Highly Cited
2009
Highly Cited
2009
Serum osteocalcin level is associated with glucose metabolism and atherosclerosis parameters in type 2 diabetes mellitus.
CONTEXT Recent animal studies showed that osteocalcin action is related to not only bone metabolism but also glucose metabolism… (More)
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Highly Cited
2009
Highly Cited
2009
The relationship of serum osteocalcin concentration to insulin secretion, sensitivity, and disposal with hypocaloric diet and resistance training.
CONTEXT Bone has recently been described as exhibiting properties of an endocrine organ by producing osteocalcin that increases… (More)
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Highly Cited
2003
Highly Cited
2003
Bone recognition mechanism of porcine osteocalcin from crystal structure
Osteocalcin is the most abundant noncollagenous protein in bone, and its concentration in serum is closely linked to bone… (More)
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Highly Cited
1998
Highly Cited
1998
Fourier transform infrared microspectroscopic analysis of bones of osteocalcin-deficient mice provides insight into the function of osteocalcin.
Osteocalcin, the gamma-carboxyglutamic acid-containing protein, which in most species is the predominant noncollagenous protein… (More)
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Highly Cited
1997
Highly Cited
1997
Targeted Disruption of Cbfa1Results in a Complete Lack of Bone Formation owing to Maturational Arrest of Osteoblasts
A transcription factor, Cbfa1, which belongs to the runt-domain gene family, is expressed restrictively in fetal development. To… (More)
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Highly Cited
1996
Highly Cited
1996
Increased bone formation in osteocalcin-deficient mice
VERTEBRATES constantly remodel bone. The resorption of preexisting bone by osteoclasts and the formation of new bone by… (More)
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Highly Cited
1992
Highly Cited
1992
Contribution of trans-acting factor alleles to normal physiological variability: vitamin D receptor gene polymorphism and circulating osteocalcin.
Osteocalcin, the most abundant noncollagenous protein in bone, is a marker of bone turnover in normal and disease states. Its… (More)
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Highly Cited
1985
Highly Cited
1985
Osteocalcin in human serum: a circadian rhythm.
Osteocalcin, the vitamin K-dependent protein synthesized in bone, is found in blood. The level of circulating osteocalcin has… (More)
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