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Organic Cation Transporter 1

Known as: Transporter, SLC22A1, OCT1 Protein, OCT1 Transport Protein 
An organic cation transporter found in kidney. It is localized to the basal lateral membrane and is likely to be involved in the renal secretion of… 
National Institutes of Health

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In BloodProcess of secretionSLC22A1 geneagonists

Papers overview

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2019
2019
Dissecting the Contribution of OATP1B1 to Hepatic Uptake of Statins Using the OATP1B1 Selective Inhibitor Estropipate.
Identification of a selective inhibitor of organic anion transporting polypeptide (OATP) 1B1 is critical in order to determine… 
2019
2019
Pharmacokinetic Interaction of Green Rooibos Extract With Atorvastatin and Metformin in Rats
An aspalathin-rich green rooibos extract (Afriplex GRT™) has demonstrated anti-diabetic and hypolipidemic properties, while also… 
2017
2017
Developmental Changes in Hepatic Organic Cation Transporter OCT1 Protein Expression from Neonates to Children
Organic cation transporter 1 (OCT1) plays an important role in the disposition of clinically important drugs, and the capacity of… 
2017
2017
Response to “Tenofovir Disoproxil Fumarate Is Not an Inhibitor of Human Organic Cation Transporter 1”
On the basis of experiments reported in their letter, Shen and coworkers concluded that tenofovir disoproxil fumarate (TDF) is… 
2017
2017
Physiologically Based Pharmacokinetic Modeling of Transporter-Mediated Hepatic Clearance and Liver Partitioning of OATP and OCT Substrates in Cynomolgus Monkeys
In the present investigations, we evaluate in vitro hepatocyte uptake and partitioning for the prediction of in vivo clearance… 
2015
2015
Multidrug and toxin extrusion 1 and human organic cation transporter 1 polymorphisms in patients with castration-resistant prostate cancer receiving metformin (SAKK 08/09)
Background:This study was initiated to explore the impact of organic cation transporter 1 (OCT1) and multidrug and toxin… 
2014
2014
POLYMORPHISM OF ORGANIC CATION TRANSPORTER 1 (OCT1 ) IN INDONESIAN CANCER PATIENTS
Objective : Organic Cation Transporter1 (OCT1) , was known as the highly polymorphism of polyspesific transporter. The genetic… 
2012
2012
Effect of cimetidine on pentamidine induced hyperglycemia in rats.
2009
2009
Characterization of Human Organic Cation Transporter 1 ( OCT 1 / SLC 22 A 1 )-and OCT 2 ( SLC 22 A 2 )-Mediated Transport
  • 2009
  • Corpus ID: 935026
1-(2-Methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)4,9-dihydro-1H-naphtho[2,3-d]imidazolium bromide (YM155 monobromide… 
2004
2004
PharmGKB Update: III. Genetic Variants of SLC22A1, Solute Carrier Family 22 (Organic Cation Transporter), Member 1
Category: Genotype PharmGKB Submission Number: PS203001 Date of Submission: June 16, 2003 Project: Pharmacogenetics of… 
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