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Org 6368

Known as: Org-6368 
 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Pancuronium
analogs & derivatives

Papers overview

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1990
1990
Hepatic transport mechanisms for bivalent organic cations. Subcellular distribution and hepato-biliary concentration gradients of some steroidal muscle relaxants.
In order to characterize the hepato-biliary transport of bivalent cations in more detail, the subcellular distribution of three… Expand
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1989
1989
A model for determining the influence of hepatic uptake of nondepolarizing muscle relaxants in the pig.
Hepatic uptake and distribution of nondepolarizing muscle relaxants in pigs was investigated. A portocaval shunt preparation… Expand
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1987
1987
Comparative neuromuscular blocking effects of vecuronium, pancuronium, Org 6368 and suxamethonium in the anaesthetized domestic pig.
The neuromuscular blocking and cardiovascular effects of three competitive neuromuscular blocking drugs, vecuronium, pancuronium… Expand
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1981
1981
Mechanisms underlying the prolonged duration of action of muscle relaxants caused by extrahepatic cholestasis.
The neuromuscular blocking effects of Org 6368 and Org NC 45 were studied in rats with experimental cholestasis and in controls… Expand
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1981
1981
Bile salts and neuromuscular blocking agents.
The influence of the primary bile salts taurocholate and chenodeoxycholate on the neuromuscular blockade of the non-depolarizing… Expand
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1980
1980
A new method for studying the relationship between hepatic uptake of drugs and their pharmacodynamic effects in anaesthetized cats.
1 A new in vivo experimental method is described whereby the liver can be temporarily excluded from the general circulation by… Expand
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1980
1980
Effect of experimental cholestasis on neuromuscular blocking drugs in cats.
Pancuronium, Org 6368 and gallamine were compared in control cats and in cats with experimental cholestasis. A decrease in the… Expand
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1979
1979
Prolongation by bile salts of the duration of action of a steroidal neuromuscular blocking agent.
The influence of bile salts on the duration of action of the steroidal non-depolarizing neuromuscular blocking agent ORG 6368 was… Expand
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1975
1975
On the pharmacology of Org 6338 (2beta, 16beta-dipiperidino - 5alpha - androstan - 3alpha - ol acetate dimethobromide), a new steroidal neuromuscular blocking agent.
Org 6368 is a homologue of pancuronium bromide. Its interactions with other agents in the cat sciatic nerve-gastrocnemius muscle… Expand
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