Org 31710

SummaryAntiprogestins have been largely utilized in reproductive medicine, yet their repositioning for oncologic use is rapidly… Expand

Progesterone (P4) antagonizes estradiol (E2) in synaptic remodeling in the hippocampus during the rat estrous cycle. To further… Expand

ORG 31710 and ORG 33628 were used in studies aiming to control vaginal bleeding in combination with progestagen-only… Expand

OBJECTIVE To investigate the effect of the anti-P Org 31710 on human blastocyst attachment to cultured endometrial epithelial… Expand

OBJECTIVE To investigate if progesterone receptor (PR)-mediated effects are involved in regulating the susceptibility to… Expand

Abstract Progesterone (P) is one of several local mediators in the ovulatory cascade in the rat. The precise mechanisms of action… Expand

Org 31710 and Org 33628 are two highly selective progesterone receptor modulators (PRMs) with respect to their anti… Expand

Endocrine and ultrasound effects were studied of an intermittent (every 28 days) oral administration of 150 mg of the anti… Expand

To investigate ovulation, an in vitro model with cultured mouse follicles was developed and compared with an in vivo ovulation… Expand

Org 31710 and Org 31806 are new antiprogestagens. These compounds were tested for their binding affinity to various steroid… Expand