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Org 31710

Known as: Org-31710 
National Institutes of Health

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2 relations

Broader (2)

EstrenesFurans

Papers overview

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2011
2011
Growth inhibition induced by antiprogestins RU-38486, ORG-31710, and CDB-2914 in ovarian cancer cells involves inhibition of cyclin dependent kinase 2
SummaryAntiprogestins have been largely utilized in reproductive medicine, yet their repositioning for oncologic use is rapidly… 
2009
2009
Progesterone influence on neurite outgrowth involves microglia.
Progesterone (P4) antagonizes estradiol (E2) in synaptic remodeling in the hippocampus during the rat estrous cycle. To further… 
Review
2005
Review
2005
ORG 33628 and ORG 31710 to control vaginal bleeding in progestin-only contraceptive regimens.
ORG 31710 and ORG 33628 were used in studies aiming to control vaginal bleeding in combination with progestagen-only… 
2005
2005
The antiprogesterone Org 31710 inhibits human blastocyst-endometrial interactions in vitro.
Highly Cited
2001
Highly Cited
2001
Progesterone receptor antagonists Org 31710 and RU 486 increase apoptosis in human periovulatory granulosa cells.
2000
2000
Preclinical experience with two selective progesterone receptor modulators on breast and endometrium
2000
2000
Time-Dependent Ovulation Inhibition of a Selective Progesterone-Receptor Antagonist (Org 31710) and Effects on Ovulatory Mediators in the In Vitro Perfused Rat Ovary1
Abstract Progesterone (P) is one of several local mediators in the ovulatory cascade in the rat. The precise mechanisms of action… 
2000
2000
Single monthly administration of the anti-progestagen Org 31710 in users of the 75 microg desogestrel progestagen-only pill: effects on pituitary-ovarian activity.
Endocrine and ultrasound effects were studied of an intermittent (every 28 days) oral administration of 150 mg of the anti… 
Highly Cited
1999
Highly Cited
1999
Development and characterization of an in vitro ovulation model using mouse ovarian follicles.
To investigate ovulation, an in vitro model with cultured mouse follicles was developed and compared with an in vivo ovulation… 
Highly Cited
1994
Highly Cited
1994
Pharmacology of two new very selective antiprogestagens: Org 31710 and Org 31806.
Org 31710 and Org 31806 are new antiprogestagens. These compounds were tested for their binding affinity to various steroid… 
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