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A prospective, randomized, assessor-blind, multicentre study comparing recombinant and urinary follicle stimulating hormone (Puregon versus Metrodin) in in-vitro fertilization.
Recombinant FSH (Puregon) is more effective than urinary FSH in inducing multifollicular development and achieving an ongoing pregnancy in infertile women undergoing in-vitro fertilization. Expand
Ovarian function with a novel combined contraceptive vaginal ring.
NuvaRing is a highly effective, reversible method of hormonal contraception, at least until the stage of a 13 mm dominant follicle, is prevented and as little as 3 consecutive days of NuvaRing use interferes with follicle growth. Expand
Tibolone: influence on markers of cardiovascular disease.
- N. Bjarnason, K. Bjarnason, J. Haarbo, H. Bennink, C. Christiansen
- The Journal of clinical endocrinology and…
- 1 June 1997
The overall effect on hemostatic factors of the present doses of tibolone in healthy, late postmenopausal women tends towards increased fibrinolysis and unchanged coagulation, which may be beneficial and might theoretically counterbalance the potentially negative effect of the decrease in high density lipoprotein cholesterol. Expand
Double-blind, placebo-controlled study of the effects of tibolone on bone mineral density in postmenopausal osteoporotic women with and without previous fractures.
- P. Pavlov, J. Ginsburg, P. Kicovic, D. B. van der Schaaf, G. Prelevic, H. Bennink
- Gynecological endocrinology : the official…
- 1 August 1999
It is found that tibolone 2.5 mg induces significant increases of trabecular and cortical bone mass in elderly postmenopausal osteoporotic women with and without previous fractures and a significant fall in bone biochemistry parameters showed that tIBolone inhibits osteoclastic activity. Expand
Effects of two doses of tibolone on trabecular and cortical bone loss in early postmenopausal women: a two-year randomized, placebo-controlled study.
Tibolone prevents early postmenopausal bone loss by inducing an increase in trabecular and phalangeal BD as compared to pretreatment values after 2 years of tibolones. Expand
A 4-year pilot study on the efficacy and safety of Implanon, a single-rod hormonal contraceptive implant, in healthy women in Thailand.
- O. Kiriwat, A. Patanayindee, S. Koetsawang, T. Korver, H. Bennink
- The European journal of contraception…
- 1 June 1998
Implanon demonstrated excellent contraceptive efficacy and was well tolerated during up to 4 years of use, and the vaginal bleeding pattern was variable and was characterized by relatively few bleeding events, but proved acceptable to most subjects. Expand
Effect of Implanon use on selected parameters of thyroid and adrenal function.
In the Norplant group, sex hormone-binding globulin levels decreased, whereas increased levels were found in the Implanon users at the end of 2 years, lending support to the fact that etonogestrel, released from Implan on implants, is significantly less androgenic than levonorgestrel. Expand
The effect of add-back treatment with tibolone (Livial) on patients treated with the gonadotropin-releasing hormone agonist triptorelin (Decapeptyl).
The addition of tibolone to GnRH-a treatment reduces the bone loss and vasomotor symptoms that normally occur with Gn RH-a, thus making long-term treatment with Gnrh-a safer and more acceptable. Expand
Lowering of HDL cholesterol in post-menopausal women by tibolone is not associated with changes in cholesterol efflux capacity or paraoxonase activity.
It is concluded that changes in insulin do not contribute to the lowering of HDL cholesterol by tibolone, and putatively anti-atherogenic activities of HDL remained unchanged. Expand
Effect of hormone replacement therapy on lipids in perimenopausal and early postmenopausal women.
Treatment of perimenopausal and early postmenopausal women with 17beta-E-D or CEE-N changes their lipid-profile in a potentially anti-atherogenic direction, and changes appear to be more pronounced in post menopausal women compared to perimenographic women. Expand