Orazamide

Known as: AICA orotate, 4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-, Compd. With 5-amino-1H-imidazole-4-carboxamide (1:1), Dihydrate, 1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylic acid cpd with 5-amino-1H-imidazole-4-carboxamide 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1959-2017
0102019592017

Papers overview

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Highly Cited
2003
Highly Cited
2003
BACKGROUND The AMP-activated protein kinase (AMPK) cascade is a sensor of cellular energy charge that acts as a 'metabolic master… (More)
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Highly Cited
2003
Highly Cited
2003
We have recently shown that conditions known to activate AMP-activated protein kinase (AMPK) in primary beta-cells can trigger… (More)
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Highly Cited
2002
Highly Cited
2002
Metformin, a drug widely used to treat type 2 diabetes, was recently shown to activate the AMP-activated protein kinase (AMPK) in… (More)
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Highly Cited
2002
Highly Cited
2002
Protein synthesis, in particular peptide-chain elongation, consumes cellular energy. Anoxia activates AMP-activated protein… (More)
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Highly Cited
2002
Highly Cited
2002
5'-AMP-activated protein kinase (AMPK) functions as a metabolic switch in mammalian cells and can be artificially activated by 5… (More)
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Highly Cited
2002
Highly Cited
2002
Stimulation of AMP-activated protein kinase (AMPK) in skeletal muscle has been correlated with an increase in glucose transport… (More)
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Highly Cited
1999
Highly Cited
1999
It has previously been reported that exercise causes an increase in glucose uptake in skeletal muscle and also an increase in 5… (More)
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Highly Cited
1999
Highly Cited
1999
AMP-activated kinase (AMPK) is activated in response to metabolic stresses that deplete cellular ATP, and in both liver and… (More)
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Highly Cited
1998
Highly Cited
1998
The role of the AMP-activated protein kinase (AMPK) cascade in the glucose-sensitive pancreatic beta cell lines HIT-T15 and INS-1… (More)
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Highly Cited
1997
Highly Cited
1997
5-Aminoimidazole-4-carboxamide ribonucleoside (AICAR) has previously been reported to be taken up into cells and phosphorylated… (More)
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