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Orazamide

Known as: AICA orotate, 4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-, Compd. With 5-amino-1H-imidazole-4-carboxamide (1:1), Dihydrate, 1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylic acid cpd with 5-amino-1H-imidazole-4-carboxamide 
National Institutes of Health

Related topics

Related topics

3 relations

Narrower (1)

Aicamine

Broader (1)

Aminoimidazole Carboxamide
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Intravenous AICAR During Hyperinsulinemia Induces Systemic Hemodynamic Changes but Has No Local Metabolic Effect
AMPK activation may stimulate glucose uptake in skeletal muscle, but the results in humans have so far been inconclusive. The… 
2010
2010
Analysis and stability study of temozolomide using capillary electrophoresis.
Highly Cited
2010
Highly Cited
2010
Germline deletion of AMP‐activated protein kinase β subunits reduces bone mass without altering osteoclast differentiation or function
Since AMP‐activated protein kinase (AMPK) plays important roles in modulating metabolism in response to diet and exercise, both… 
2005
2005
AICAR suppresses IL-2 expression through inhibition of GSK-3 phosphorylation and NF-AT activation in Jurkat T cells.
Highly Cited
2004
Highly Cited
2004
AG2034: a novel inhibitor of glycinamide ribonucleotide formyltransferase
SummaryThe glycinamide ribonucleotide formyltransferase (GARFT) inhibitor, 4-[2-(2-amino-4-oxo-4,6,7,8-tetrahydro-3H-pyrimidino[5… 
Highly Cited
2003
Highly Cited
2003
Acadesine activates AMPK and induces apoptosis in B-cell chronic lymphocytic leukemia cells but not in T lymphocytes.
Acadesine, 5-aminoimidazole-4-carboxamide (AICA) riboside, induced apoptosis in B-cell chronic lymphocytic leukemia (B-CLL) cells… 
Highly Cited
1986
Highly Cited
1986
Sodium/calcium exchange and intracellular calcium buffering in ferret myocardium: an ion‐sensitive micro‐electrode study.
Measurements of the intracellular activity of Ca (aiCa), Na (aiNa) and H (pHi) ions have been made with resin‐filled ion… 
Highly Cited
1982
Highly Cited
1982
Changes in intracellular Ca2+ activity with stimulation in sheep cardiac Purkinje strands.
One hypothesis to explain increased contraction strength with increased stimulation rate in heart muscle requires that… 
Highly Cited
1980
Highly Cited
1980
Sodium-calcium exchange in rabbit heart muscle cells: direct measurement of sarcoplasmic Ca2+ activity.
Calcium ion-selective microelectrodes made with Simon's neutral carrier were used to measure simultaneously sarcoplasmic Ca2… 
1976
1976
Synthesis and antiviral and antimicrobial activity of certain 1-beta-D-ribofuranosyl-4,5-disubstituted imidazoles.
Starting with AICA ribonucleoside the following nucleosides were prepared. Methyl 5-amino-1-(2,3,5-tri-O-acetyl-beta-D… 
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